Gene: Zc3h3
Official Full Name: zinc finger CCCH type containing 3provided by MGI
Gene Summary: Enables R-SMAD binding activity. Acts upstream of or within mRNA 3'-end processing and positive regulation of activin receptor signaling pathway. Part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in central nervous system and genitourinary system. Orthologous to human ZC3H3 (zinc finger CCCH-type containing 3). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01086 | Zc3h3 Knockout cell line (CT26.WT) | Mouse | Zc3h3 | 1:3~1:4 | Negative | Online Inquiry |
Zc3h3 Gene Knockout Cell Lines are genetically modified cell lines that have undergone targeted disruption of the Zc3h3 gene, a gene known to play a critical role in cellular processes such as RNA metabolism and transcription regulation. By creating a knockout model of Zc3h3, researchers can precisely study the gene's function and its implications in various biological contexts, including stem cell differentiation, tumorigenesis, and immune responses.
The primary mechanism of these knockout cell lines involves CRISPR-Cas9 technology, which allows for specific and efficient disruption of the Zc3h3 gene. This precise gene editing tool enables the elimination of Zc3h3 expression, allowing researchers to observe phenotypic and molecular changes resulting from the loss of this gene. Using these cell lines, scientists can conduct a range of assays, such as gene expression profiling, cellular signaling studies, and functional analyses, to uncover the roles Zc3h3 plays in health and disease.
The scientific importance of Zc3h3 Gene Knockout Cell Lines extends into research and clinical settings, where they can facilitate the exploration of gene function and provide insights into various pathological conditions, including cancers and genetic disorders. In particular, researchers can utilize these cell lines to develop and validate therapeutic approaches targeting the pathways impacted by Zc3h3 disruption.
Compared to other gene knockout models, the Zc3h3 cell lines offer enhanced specificity and efficiency due to the favorable characteristics of CRISPR-based modifications. Additionally, these cell lines are validated and optimized for growth and transfection across various research laboratories, ensuring reliable results in experimental workflows.
For researchers and clinicians seeking to unravel complex biological pathways, Zc3h3 Gene Knockout Cell Lines represent an invaluable resource for advancing knowledge in functional genomics. Our commitment to quality and innovation assures that every cell line provided is thoroughly characterized, ensuring users receive reliable tools to propel their research forward. With our extensive expertise in biological products, we are dedicated to supporting scientific discovery and providing researchers with the resources they need to make significant advancements in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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