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ZNHIT1 Knockout Cell Lines

Gene: ZNHIT1

Official Full Name: zinc finger HIT-type containing 1provided by HGNC

Gene Summary: Enables histone binding activity. Involved in muscle cell differentiation and positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04894 ZNHIT1 Knockout cell line (HeLa) Human ZNHIT1 1:3~1:6 Negative Online Inquiry
KO04895 ZNHIT1 Knockout cell line (HCT 116) Human ZNHIT1 1:2~1:4 Negative Online Inquiry
KO04896 ZNHIT1 Knockout cell line (HEK293) Human ZNHIT1 1:3~1:6 Negative Online Inquiry
KO04897 ZNHIT1 Knockout cell line (A549) Human ZNHIT1 1:3~1:4 Negative Online Inquiry

Background

ZNHIT1 Gene Knockout Cell Lines represent a significant advancement in genetic research and functional studies. These cell lines are specifically designed to eliminate the expression of the ZNHIT1 gene, which encodes a protein implicated in various cellular processes, including proliferation, differentiation, and response to stress. By creating a knockout model, researchers can investigate the gene's role in pathophysiological conditions, enabling a deeper understanding of diseases such as cancer or metabolic disorders.

The primary function of ZNHIT1 Gene Knockout Cell Lines is to facilitate studies on gene function and regulation. The knockout mechanism employs CRISPR-Cas9 technology, which introduces specific mutations that disrupt the gene’s coding sequence, leading to a complete loss of function. This precise gene-editing approach allows for reproducible analyses and the opportunity to validate hypotheses related to ZNHIT1's role in cellular signaling pathways or interactions with other biomolecules.

Scientifically, these cell lines are pivotal in exploring new therapeutic targets and understanding the underlying mechanisms of diseases. Their application spans various fields, including oncology, immunology, and developmental biology. Researchers can utilize these models for drug screening, biomarker discovery, or the elucidation of gene therapeutic strategies in clinical settings.

Compared to other gene knockout methods, ZNHIT1 Gene Knockout Cell Lines are advantageous due to their high specificity, efficiency, and the support of established cell line backgrounds that mimic in vivo conditions more closely. They are verified to maintain genetic stability and consistent phenotypic characteristics, providing reliable data across experiments.

For researchers and clinicians, these cell lines represent a crucial tool to accelerate investigations and develop innovative solutions across various biomedical landscapes. The ability to study ZNHIT1 function in a controlled environment enhances the potential for breakthroughs in both basic and translational research.

Our company specializes in producing high-quality biological products, leveraging cutting-edge technologies to support the scientific community. With rigorous quality control and a commitment to advancing research, we ensure that our ZNHIT1 Gene Knockout Cell Lines empower your discoveries and enhance your research capabilities.

Please note that all services are for research use only. Not intended for any clinical use.

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