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ZNF805 Knockout Cell Lines

Gene: ZNF805

Official Full Name: zinc finger protein 805provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11962 ZNF805 Knockout cell line (HeLa) Human ZNF805 1:3~1:6 Negative Online Inquiry
KO11963 ZNF805 Knockout cell line (HCT 116) Human ZNF805 1:2~1:4 Negative Online Inquiry
KO11964 ZNF805 Knockout cell line (HEK293) Human ZNF805 1:3~1:6 Negative Online Inquiry
KO11965 ZNF805 Knockout cell line (A549) Human ZNF805 1:3~1:4 Negative Online Inquiry

Background

ZNF805 Gene Knockout Cell Lines are specifically engineered cellular models where the ZNF805 gene has been inactivated or "knocked out" using precise gene-editing technologies such as CRISPR/Cas9. ZNF805, known for its involvement in neurodevelopment and potentially linked to various neuropsychiatric disorders, provides a unique insight into the fundamental biological processes underlying gene function. These cell lines are vital for elucidating the role of ZNF805 in cellular mechanisms, allowing researchers to examine its contribution to gene regulation, differentiation, and response to external stimuli.

The key function of ZNF805 Gene Knockout Cell Lines lies in their ability to provide a controlled biological environment where the effects of the absence of ZNF805 can be studied. This includes understanding alterations in signaling pathways, gene expression profiles, and cellular behavior that may mimic certain disease conditions. The knockout of ZNF805 can facilitate research into its potential roles in conditions such as schizophrenia, depression, or autism spectrum disorders, making these cell lines essential tools in both basic and translational research.

From a scientific standpoint, these cell lines offer substantial advantages in pharmacological testing and therapeutic approaches, including drug discovery and gene therapy innovations. By utilizing these knockout models, researchers can better understand drug targets, assess therapeutic efficacy, and screen for compounds that could restore normal function or correct dysregulation linked to ZNF805.

Compared to alternative cell lines that retain the ZNF805 gene, these knockout models provide a clear advantage by eliminating confounding variables. This specificity allows for more precise studies, increasing confidence in the results. Additionally, they can be used in combination with other gene-editing technologies to explore multifactorial biological systems.

The value of ZNF805 Gene Knockout Cell Lines extends to researchers and clinicians who seek to unravel the complexities of gene function and its association with disease. Their utility in identifying potential biomarkers and understanding drug response mechanisms places them at the forefront of genetic research.

Our company is dedicated to advancing research through innovative biological products, including cutting-edge cellular models like the ZNF805 Gene Knockout Cell Lines. With a strong commitment to quality and scientific excellence, we aim to support the research community in pioneering discoveries that have the potential to translate into effective clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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