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ZNF7 Knockout Cell Lines

Gene: ZNF7

Official Full Name: zinc finger protein 7provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in membrane. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34763 ZNF7 Knockout cell line (HeLa) Human ZNF7 1:3~1:6 Negative Online Inquiry
KO34764 ZNF7 Knockout cell line (HCT 116) Human ZNF7 1:2~1:4 Negative Online Inquiry
KO34765 ZNF7 Knockout cell line (HEK293) Human ZNF7 1:3~1:6 Negative Online Inquiry
KO34766 ZNF7 Knockout cell line (A549) Human ZNF7 1:3~1:4 Negative Online Inquiry

Background

ZNF7 Gene Knockout Cell Lines are specialized cellular models designed to eliminate the expression of the zinc finger protein 7 (ZNF7) gene, which plays a crucial role in various cellular processes, including transcriptional regulation and DNA damage response. These cell lines are developed using state-of-the-art CRISPR/Cas9 gene-editing technology, enabling precise and efficient knockout of the ZNF7 gene. The resultant knockout cells provide an unparalleled tool for investigating the biological functions of ZNF7 and its implications in cellular pathways.

The primary mechanism by which ZNF7 gene knockout cell lines operate is through the targeted disruption of the ZNF7 gene, leading to the absence of the protein in cellular environments. This allows researchers to study the resultant phenotypic and functional changes, thereby clarifying the roles ZNF7 plays in cellular growth, differentiation, stress response, and apoptosis. Such insights are critical for understanding how aberrancies in ZNF7 function may contribute to tumorigenesis or various diseases.

In the realm of scientific research and clinical applications, ZNF7 gene knockout cell lines serve as pivotal tools for drug discovery, genetic studies, and therapeutic interventions. They offer researchers the opportunity to create models of disease that replicate the loss-of-function mutations observed in certain cancers, thus facilitating the development of targeted therapies and enhancing our understanding of cancer biology.

Key advantages of ZNF7 gene knockout cell lines include their high specificity due to the precise nature of CRISPR technology, which minimizes off-target effects observed in other gene-editing methods. Additionally, these cell lines can be easily integrated into existing experimental workflows, making them accessible and flexible for various applications.

For researchers and clinicians, ZNF7 gene knockout cell lines represent an invaluable asset in the pursuit of novel treatments and a deeper understanding of gene function in health and disease. By employing these knockout models, users can advance their research agendas and contribute to pioneering breakthroughs in the life sciences.

Our company specializes in developing high-quality cell lines that empower scientific discovery. With a commitment to excellence and innovation, we provide top-tier products and services to support your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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