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ZNF620 Knockout Cell Lines

Gene: ZNF620

Official Full Name: zinc finger protein 620provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21223 ZNF620 Knockout cell line (HeLa) Human ZNF620 1:3~1:6 Negative Online Inquiry
KO21224 ZNF620 Knockout cell line (HCT 116) Human ZNF620 1:2~1:4 Negative Online Inquiry
KO21225 ZNF620 Knockout cell line (HEK293) Human ZNF620 1:3~1:6 Negative Online Inquiry
KO21226 ZNF620 Knockout cell line (A549) Human ZNF620 1:3~1:4 Negative Online Inquiry

Background

ZNF620 Gene Knockout Cell Lines are specifically engineered cellular models in which the ZNF620 gene has been inactivated, allowing researchers to study the biological functions and regulatory mechanisms associated with this gene. The ZNF620 gene encodes a zinc finger protein that plays a critical role in various cellular processes, including gene expression regulation, cell differentiation, and development. By utilizing these knockout cell lines, investigators can elucidate the specific contributions of ZNF620 in both normal physiological contexts and various pathophysiological conditions.

The key function of ZNF620 Gene Knockout Cell Lines lies in their ability to produce a controlled environment in which the absence of ZNF620 can be analyzed. This is achieved through advanced gene-editing technologies such as CRISPR/Cas9, which induces double-strand breaks at targeted locations in the genome, leading to gene disruption. By examining the resultant phenotypic and molecular alterations, researchers can explore the gene's role in signaling pathways, transcriptional regulation, and interactions with other genes and proteins.

Scientifically, the importance of ZNF620 Gene Knockout Cell Lines extends to their applications in both basic research and clinical settings. These models can significantly enhance understanding of diseases linked to ZNF620 dysregulation, such as certain cancers and developmental disorders, thereby facilitating the discovery of novel therapeutic targets and biomarkers. The ability to conduct high-throughput screening and functional assays within these cell lines accelerates the process of drug development and precision medicine.

Compared to alternative models such as wild-type cell lines or in vivo systems, ZNF620 Gene Knockout Cell Lines offer precise control over genetic variables, leading to reproducible and reliable experimental outcomes. Additionally, the reduction in genetic variability minimizes confounding factors that could influence experimental results, thereby providing enhanced clarity and insight into ZNF620 function.

For researchers and clinicians alike, the value of ZNF620 Gene Knockout Cell Lines lies not only in their innovative design and specificity but also in their capacity to provide critical insights into complex biological processes. Our company is committed to advancing scientific knowledge through high-quality biological products, leveraging expertise in genetic engineering and cell line development to support researchers in their quest for discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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