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ZNF589 Knockout Cell Lines

Gene: ZNF589

Official Full Name: zinc finger protein 589provided by HGNC

Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22590 ZNF589 Knockout cell line (HeLa) Human ZNF589 1:3~1:6 Negative Online Inquiry
KO22591 ZNF589 Knockout cell line (HCT 116) Human ZNF589 1:2~1:4 Negative Online Inquiry
KO22592 ZNF589 Knockout cell line (HEK293) Human ZNF589 1:3~1:6 Negative Online Inquiry
KO22593 ZNF589 Knockout cell line (A549) Human ZNF589 1:3~1:4 Negative Online Inquiry

Background

ZNF589 Gene Knockout Cell Lines are specialized cellular models engineered to facilitate the study of the ZNF589 gene’s role in various biological processes. The ZNF589 gene encodes a zinc finger protein that is implicated in diverse cellular functions, including transcriptional regulation and developmental processes. Creating knockout cell lines allows researchers to investigate the phenotypic consequences resulting from the loss of this gene, providing insights into its specific biological functions and pathways.

The key mechanism of action involves the use of CRISPR-Cas9 technology, which enables precise editing of the genomic DNA, leading to the disruption of the ZNF589 gene. Upon creating these knockout models, scientists can assess alterations in cell behavior, gene expression patterns, and various functional assays to understand the implications of ZNF589 deficiency. This approach is invaluable in elucidating gene functions and their impacts on cellular homeostasis and disease mechanisms.

The scientific importance of ZNF589 Gene Knockout Cell Lines extends to both research and clinical applications. These models are essential for studying diseases where dysregulation of the ZNF589 gene plays a role, such as various cancers or developmental disorders. They provide a robust platform for drug discovery and therapeutic interventions by enabling high-throughput screening of potential compounds that could target related pathways.

Unlike traditional cell lines that may express the ZNF589 gene, these knockout lines offer researchers a highly controlled environment to study the gene's absence, highlighting the specific biological outcomes without confounding factors. This specificity is crucial in providing clear interpretation of experimental results, thereby enhancing the reproducibility and reliability of research findings.

ZNF589 Gene Knockout Cell Lines are therefore an indispensable tool for researchers looking to deepen their understanding of gene function and regulation, with significant implications for therapeutic development. Our company prides itself on its expertise in genetic engineering and cell line development, ensuring that our products meet rigorous scientific standards while providing cutting-edge solutions tailored to the needs of the research community. We are committed to advancing biological research through exceptional products that empower scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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