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ZNF512B Knockout Cell Lines

Gene: ZNF512B

Official Full Name: zinc finger protein 512Bprovided by HGNC

Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of miRNA transcription. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12192 ZNF512B Knockout cell line (HeLa) Human ZNF512B 1:3~1:6 Negative Online Inquiry
KO12193 ZNF512B Knockout cell line (HCT 116) Human ZNF512B 1:2~1:4 Negative Online Inquiry
KO12194 ZNF512B Knockout cell line (HEK293) Human ZNF512B 1:3~1:6 Negative Online Inquiry
KO12195 ZNF512B Knockout cell line (A549) Human ZNF512B 1:3~1:4 Negative Online Inquiry

Background

ZNF512B gene knockout cell lines are genetically engineered cellular models designed to explore the functional role of the ZNF512B gene in various biological processes. Utilizing CRISPR-Cas9 gene editing technology, these knockout cell lines exhibit a complete disruption of the ZNF512B gene, allowing for the assessment of its contributions to cellular functions, pathologies, and response mechanisms in specific environments. This tool acts as a pivotal resource for dissecting the impact of ZNF512B on gene regulation, cellular development, and disease states, including cancer and metabolic disorders.

The key function of these knockout cell lines lies in their capacity to provide a clear, controlled environment for researchers to evaluate the effects of ZNF512B depletion. By elucidating the downstream effects of this gene's absence, scientists can uncover novel pathways and interactions that may be critical for understanding tumorigenesis or other pathological conditions. Additionally, these cell lines facilitate high-throughput screening processes for potential therapeutic targets, enhancing their utility in drug discovery and functional genomics.

The scientific importance of ZNF512B gene knockout cell lines extends to their applications in both research and clinical settings. They offer a unique perspective for investigating the mechanisms underpinning diseases where ZNF512B is implicated, serving not only as valuable references in academic studies but also enabling translational research that can lead to innovative therapeutic approaches.

Compared to traditional gene silencing approaches, such as RNA interference (RNAi), ZNF512B knockout cell lines provide a permanent and complete gene disruption, resulting in more accurate gene function assessments. This permanence allows researchers to study long-term physiological consequences and offers a distinct advantage over transient knockdown methods that may exhibit residual gene activity.

Target users, including researchers in molecular biology and clinical laboratories, will find ZNF512B gene knockout cell lines indispensable for their studies. The value of this product lies in its ability to yield clear insights into essential biological functions and disease mechanisms, ultimately paving the way for advancements in targeted therapies and precision medicine.

Our company is committed to providing high-quality, cutting-edge biological tools designed to enhance research capabilities and foster scientific discovery. With a deep understanding of molecular genetics and gene editing technologies, we empower researchers and clinicians with the products they need to drive innovation in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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