Gene: ZNF175
Official Full Name: zinc finger protein 175provided by HGNC
Gene Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34553 | ZNF175 Knockout cell line (HeLa) | Human | ZNF175 | 1:3~1:6 | Negative | Online Inquiry |
KO34554 | ZNF175 Knockout cell line (HCT 116) | Human | ZNF175 | 1:2~1:4 | Negative | Online Inquiry |
KO34555 | ZNF175 Knockout cell line (HEK293) | Human | ZNF175 | 1:3~1:6 | Negative | Online Inquiry |
KO34556 | ZNF175 Knockout cell line (A549) | Human | ZNF175 | 1:3~1:4 | Negative | Online Inquiry |
ZNF175 Gene Knockout Cell Lines represent a pioneering advancement in the toolkit of molecular biology, specifically designed to facilitate the study of the ZNF175 gene and its associated functions. These cell lines have been meticulously engineered through CRISPR/Cas9 technology to exhibit a complete knockout of the ZNF175 gene, allowing researchers to explore the gene’s role in various biological processes and its implication in diseases, particularly neurodevelopmental disorders and cancers.
The primary function of these cell lines is to serve as a reliable model for functional assays, enabling the elucidation of ZNF175’s mechanisms of action. By knocking out this specific gene, researchers can observe resultant phenotypic changes, gene expression alterations, and pathways affected, thereby contributing significantly to the understanding of gene regulation and cellular behavior in both normal and pathological states.
In research and clinical settings, ZNF175 Gene Knockout Cell Lines hold substantial scientific importance. They enable in-depth studies of transcriptional regulation, gene interaction networks, and cellular responses to various stimuli, thus promoting the development of targeted therapeutics. Their applications extend across fields such as cancer research, gene therapy, and drug discovery, providing a sophisticated model for preclinical trials.
A notable advantage of using these specialized cell lines lies in their uniformity and reproducibility, setting them apart from traditional methods of gene disruption that often yield variable results. This consistency ensures that researchers can attain reliable data crucial for hypothesis validation. Furthermore, the ease of use in downstream applications—be it gene expression analysis, phenotypic assays, or drug screening—positions ZNF175 Gene Knockout Cell Lines as a valuable asset in any laboratory.
For researchers and clinicians focused on harnessing genetic insights to improve patient outcomes, these cell lines offer a pathway to groundbreaking discoveries. Our company, with a commitment to advancing biological research, combines expertise in genetic engineering with rigorous quality control to deliver high-fidelity knockout models, empowering the scientific community to explore new frontiers in gene function and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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