Home / ZNF146 Knockout Cell Lines

ZNF146 Knockout Cell Lines

Gene: ZNF146

Official Full Name: zinc finger protein 146provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34592 ZNF146 Knockout cell line (HeLa) Human ZNF146 1:3~1:6 Negative Online Inquiry
KO34593 ZNF146 Knockout cell line (HCT 116) Human ZNF146 1:2~1:4 Negative Online Inquiry
KO34594 ZNF146 Knockout cell line (HEK293) Human ZNF146 1:3~1:6 Negative Online Inquiry
KO34595 ZNF146 Knockout cell line (A549) Human ZNF146 1:3~1:4 Negative Online Inquiry

Background

ZNF146 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed for the study of gene function and regulation. These engineered cell lines feature the complete knockout of the ZNF146 gene, which encodes a zinc finger protein that is implicated in various regulatory processes, including transcriptional control and cellular differentiation. By employing CRISPR-Cas9 technology for precise genomic editing, these cell lines offer researchers the ability to directly observe the effects of ZNF146 loss on cellular behavior and gene expression.

The primary function of these ZNF146 knockout cell lines lies in their utility for elucidating the biological pathways influenced by ZNF146 and for investigating its role in disease mechanisms. Researchers can achieve insights into cellular processes such as proliferation, apoptosis, and metabolic changes, accelerating the understanding of conditions where ZNF146 is dysregulated, such as certain cancers and genetic disorders.

The scientific importance of ZNF146 knockout cell lines is underscored by their applications in both basic and translational research. They facilitate gene editing experiments, drug discovery, and the development of therapeutic strategies by providing a reliable platform to assess the pharmacological or genetic effects of potential treatments.

Compared to traditional methods of gene silencing, such as RNA interference, ZNF146 knockout cell lines offer permanent gene editing, which leads to stable phenotypic changes and eliminates variability from transient transfection techniques. This allows for more reproducible results, increasing the robustness of experimental findings.

For researchers and clinicians, these cell lines are invaluable as they enable deeper insights into gene function and pathways, paving the way for innovative therapeutic approaches. Each cell line is validated for ZNF146 knockout efficiency and characterized for cellular behavior, ensuring high-quality data for users.

Leading in the field of genetic engineering, our company specializes in providing high-fidelity gene editing products and tools, ensuring that scientists have access to state-of-the-art resources for their research needs. With a commitment to excellence and innovation, we strive to support groundbreaking discoveries in molecular biology and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.