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ZMYM3 Knockout Cell Lines

Gene: ZMYM3

Official Full Name: zinc finger MYM-type containing 3provided by HGNC

Gene Summary: This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33452 ZMYM3 Knockout cell line (HeLa) Human ZMYM3 1:3~1:6 Negative Online Inquiry
KO33453 ZMYM3 Knockout cell line (HCT 116) Human ZMYM3 1:2~1:4 Negative Online Inquiry
KO33454 ZMYM3 Knockout cell line (HEK293) Human ZMYM3 1:3~1:6 Negative Online Inquiry
KO33455 ZMYM3 Knockout cell line (A549) Human ZMYM3 1:3~1:4 Negative Online Inquiry

Background

ZMYM3 Gene Knockout Cell Lines represent a significant advancement in genetic research, providing researchers with a powerful tool to study the functions and pathways of the ZMYM3 gene—a critical player in cellular processes including gene regulation and chromatin remodeling. These cell lines are engineered to have a targeted deletion of the ZMYM3 gene, allowing for detailed examination of its role in various biological contexts, such as development, disease progression, and response to treatment.

The primary function of ZMYM3 Gene Knockout Cell Lines is to facilitate the dissection of the gene's contributions to cellular mechanisms. By comparing these knockout lines with wild-type controls, researchers can assess how the absence of ZMYM3 impacts cellular proliferation, differentiation, and apoptosis. Mechanistically, the disruption of ZMYM3 is anticipated to yield insights into aberrant signaling pathways, transcriptional regulation, and protein interactions that are critical for understanding various disease states, particularly cancers where gene dysregulation is prevalent.

The scientific importance of ZMYM3 Gene Knockout Cell Lines extends into research and clinical settings, being indispensable for functional genomics studies, drug discovery, and therapeutic interventions. Researchers can utilize these models to evaluate the efficacy of potential pharmaceutical compounds and explore mechanisms of resistance in targeted therapies.

What sets ZMYM3 Gene Knockout Cell Lines apart is their specificity and reliability. Unlike alternatives that lack precise gene editing or utilize less controlled systems, these cell lines are produced through advanced CRISPR-Cas9 technology, ensuring a high degree of fidelity in the knockout. This enhances reproducibility in experiments and assures researchers of the robustness of their findings.

For researchers and clinicians focused on the implications of ZMYM3 in health and disease, these knockout cell lines offer valuable insights that can pave the way for novel therapeutic strategies and better understanding of complex biological systems.

Leveraging our company’s expertise in genetic engineering and a commitment to providing high-quality biological tools, ZMYM3 Gene Knockout Cell Lines are designed to support cutting-edge research and accelerate advancements in genomic medicine. With our extensive experience in creating precision models, we stand ready to assist the scientific community in unlocking new avenues in biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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