Home / ZKSCAN3 Knockout Cell Lines

ZKSCAN3 Knockout Cell Lines

Gene: ZKSCAN3

Official Full Name: zinc finger with KRAB and SCAN domains 3provided by HGNC

Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in lysosome organization; negative regulation of metabolic process; and regulation of DNA-templated transcription. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03647 ZKSCAN3 Knockout cell line (HeLa) Human ZKSCAN3 1:3~1:6 Negative Online Inquiry
KO03648 ZKSCAN3 Knockout cell line (HCT 116) Human ZKSCAN3 1:2~1:4 Negative Online Inquiry
KO03649 ZKSCAN3 Knockout cell line (HEK293) Human ZKSCAN3 1:3~1:6 Negative Online Inquiry
KO03650 ZKSCAN3 Knockout cell line (A549) Human ZKSCAN3 1:3~1:4 Negative Online Inquiry

Background

ZKSCAN3 Gene Knockout Cell Lines are a suite of engineered cellular models that facilitate the study of the ZKSCAN3 gene's biological functions by completely removing this gene's expression. The ZKSCAN3 gene is known to play a pivotal role in various cellular processes, including the regulation of cellular proliferation, differentiation, and apoptosis. By generating knockout models, researchers can create a controlled environment that allows for in-depth exploration into the gene's pathways and the phenotypic outcomes resulting from its absence.

The functionality of these knockout cell lines is rooted in the use of CRISPR-Cas9 technology, a widely recognized method for precise gene editing. By designing specific guide RNAs that target ZKSCAN3, the Cas9 nuclease generates double-stranded breaks in the gene, leading to disruptions that ultimately inhibit its transcription and translation. This enables scientists to observe changes in cellular behavior, signaling pathways, and gene expression profiles when ZKSCAN3 is non-functional, providing insights valuable for understanding its role in normal physiology and disease processes, including cancer and metabolic disorders.

The scientific importance of ZKSCAN3 Gene Knockout Cell Lines extends into both fundamental research and clinical settings. Researchers are utilizing these models to explore how disruption of ZKSCAN3 can affect cellular homeostasis and contribute to pathological conditions. Moreover, these cell lines serve as valuable tools for drug discovery initiatives, enabling the identification of targeted therapies that could modulate the genetic pathways influenced by ZKSCAN3 activity.

What sets ZKSCAN3 Gene Knockout Cell Lines apart from alternative models is their high specificity and reproducibility. Established using state-of-the-art gene editing techniques, these cell lines ensure consistent genetic modification and maintain authentic cellular characteristics, providing researchers with reliable data that is crucial for hypothesis testing. Additionally, they are designed to integrate seamlessly into existing experimental workflows, facilitating easier adoption for both seasoned researchers and those new to genetic manipulation techniques.

For researchers and clinicians alike, the introduction of ZKSCAN3 Gene Knockout Cell Lines represents an invaluable advancement in understanding gene function in cellular contexts. By employing this robust and precise tool, professionals can accelerate discoveries related to gene function and therapeutic intervention strategies, leading to significant advancements in the field.

Our company prides itself on its deep expertise in cellular engineering and molecular biology, striving to provide top-tier biological products tailored to meet the evolving demands of the research community. With a commitment to innovation and quality, we deliver cutting-edge tools, including the ZKSCAN3 Gene Knockout Cell Lines, that support scientific progress across diverse biological research areas.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.