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ZGLP1 Knockout Cell Lines

Gene: ZGLP1

Official Full Name: zinc finger GATA like protein 1provided by HGNC

Gene Summary: ZGLP1 encodes an evolutionary conserved transcriptional regulator with GATA-like zinc fingers. In females, it is expressed in embryonic germ cells and is essential for oogenic fate determination. It acts downstream of bone morphogenetic protein (BMP) and is involved in the regulation of genes involved in RNA processing, transcription and chromatin modification, retrotransposon regulation, meiotic cell cycle, and oocyte development. In males it is not required for the germ cell sex determination but is required by the spermatogonia for efficiently completing the meiotic prophase. [provided by RefSeq, Jul 2022]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20668 ZGLP1 Knockout cell line (HeLa) Human ZGLP1 1:3~1:6 Negative Online Inquiry
KO20669 ZGLP1 Knockout cell line (HCT 116) Human ZGLP1 1:2~1:4 Negative Online Inquiry
KO20670 ZGLP1 Knockout cell line (HEK293) Human ZGLP1 1:3~1:6 Negative Online Inquiry
KO20671 ZGLP1 Knockout cell line (A549) Human ZGLP1 1:3~1:4 Negative Online Inquiry

Background

ZGLP1 Gene Knockout Cell Lines are meticulously engineered cell lines where the ZGLP1 gene has been specifically disrupted to study the biological functions and downstream effects of this gene. Utilizing CRISPR-Cas9 technology, these knockout cell lines offer a precise mechanism to investigate the role of ZGLP1 in various cellular processes, including metabolism, signal transduction, and disease pathology. By selectively knocking out the ZGLP1 gene, researchers can elucidate its contributions to homeostasis and explore potential therapeutic targets for metabolic disorders.

The key function of ZGLP1 gene knockout cell lines lies in their ability to serve as powerful models for understanding the implications of gene loss-of-function in various biological contexts. This model can help dissect metabolic pathways, assess the gene's involvement in insulin secretion, and evaluate physiological responses to glucose fluctuations. Scientists can leverage these cell lines to facilitate drug testing, understand disease mechanisms, and develop strategies for intervention in conditions such as obesity and type 2 diabetes.

The scientific importance of ZGLP1 gene knockout cell lines is underscored by their potential applications in both research and clinical settings. These models are crucial for basic research studies aiming to decipher the molecular mechanisms underlying metabolic regulation. Additionally, they pave the way for translational research focused on the development of novel therapeutics that may restore normal function in ZGLP1-related pathways.

One of the unique selling points of our ZGLP1 gene knockout cell lines is their high specificity and efficiency, achieved through advanced knockout techniques that minimize off-target effects, ensuring reliable results. Compared to competitor products that may not offer the same level of customization or validation, our cell lines are characterized by robust quality control measures, making them an excellent choice for researchers seeking reproducible data.

Researchers and clinicians will find ZGLP1 gene knockout cell lines invaluable due to their versatility in application and their potential to unlock new insights into metabolic diseases. By using these models, users not only enhance the reproducibility and precision of their studies but can also accelerate the discovery of groundbreaking therapies.

Our company specializes in providing high-quality biological products backed by a team of experts dedicated to supporting scientific innovation and advancement. We are committed to delivering reliable models that facilitate cutting-edge research and contribute to significant advancements in biotechnology and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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