Gene: ZFPM1
Official Full Name: zinc finger protein, FOG family member 1provided by HGNC
Gene Summary: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in platelet formation; regulation of definitive erythrocyte differentiation; and regulation of gene expression. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP01358 | ZFPM1 gRNA1-gRNA2 KO plasmid | ZFPM1 | $850 | |||
KO12382 | ZFPM1 Knockout cell line (HeLa) | Human | ZFPM1 | 1:3~1:6 | Negative | Online Inquiry |
KO12383 | ZFPM1 Knockout cell line (HCT 116) | Human | ZFPM1 | 1:2~1:4 | Negative | Online Inquiry |
KO12384 | ZFPM1 Knockout cell line (HEK293) | Human | ZFPM1 | 1:3~1:6 | Negative | Online Inquiry |
KO12385 | ZFPM1 Knockout cell line (A549) | Human | ZFPM1 | 1:3~1:4 | Negative | Online Inquiry |
ZFPM1 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of the ZFPM1 gene, known to play critical roles in hematopoiesis and cardiogenesis. These knockout cell lines are generated using advanced CRISPR-Cas9 technology, which allows for precise gene editing, resulting in a loss-of-function phenotype that can be utilized for in-depth research into the biological implications of ZFPM1 deficiency.
The primary function of the ZFPM1 knockout cell lines is to serve as an experimental platform for exploring the molecular pathways influenced by the ZFPM1 protein. Without the expression of this transcriptional cofactor, researchers can investigate changes in cellular behavior, differentiation, and gene expression profiles, thus broadening their understanding of its contributions to developmental processes and disease states.
In scientific research and clinical settings, these cell lines are invaluable tools in elucidating the genetic underpinnings of various disorders, including cardiac and blood-related conditions. By manipulating the ZFPM1 gene's functionality, researchers can assess the implications of this gene in dysregulated pathways and potentially identify targeted therapeutic strategies.
Compared to other gene knockout systems, ZFPM1 Gene Knockout Cell Lines offer enhanced specificity and efficiency. They enable rapid screening and analysis of downstream effects stemming from ZFPM1 deletion—as opposed to more labor-intensive traditional knockout methods. This streamlining of the research process saves significant time and resources, allowing scientists to achieve reproducible results more swiftly.
For researchers, clinicians, and laboratories focused on genetic and cell biology, these knockout cell lines present a compelling opportunity to deepen insights into gene function and its roles in health and disease. Furthermore, the product is backed by our company’s extensive expertise in genetic engineering and commitment to high-quality bioresearch tools, ensuring that you have reliable models for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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