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ZDHHC21 Knockout Cell Lines

Gene: ZDHHC21

Official Full Name: zDHHC palmitoyltransferase 21provided by HGNC

Gene Summary: Enables palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12418 ZDHHC21 Knockout cell line (HeLa) Human ZDHHC21 1:3~1:6 Negative Online Inquiry
KO12419 ZDHHC21 Knockout cell line (HCT 116) Human ZDHHC21 1:2~1:4 Negative Online Inquiry
KO12420 ZDHHC21 Knockout cell line (HEK293) Human ZDHHC21 1:3~1:6 Negative Online Inquiry
KO12421 ZDHHC21 Knockout cell line (A549) Human ZDHHC21 1:3~1:4 Negative Online Inquiry

Background

ZDHHC21 Gene Knockout Cell Lines are advanced cellular models specifically engineered for studying the ZDHHC21 gene, which is implicated in multiple biological processes, including membrane protein palmitoylation and cellular signaling pathways. These cell lines have been created using cutting-edge CRISPR-Cas9 gene-editing technology that effectively disrupts the ZDHHC21 gene, allowing for comprehensive investigations into the gene's functional roles and its contributions to various pathophysiological conditions.

The primary function of ZDHHC21 involves facilitating the addition of palmitoyl groups to cysteine residues on target proteins, a post-translational modification that significantly influences protein localization and function. By utilizing these knockout cell lines, researchers can delve into the mechanistic pathways modulated by ZDHHC21, providing insights into its relevance in neurodevelopmental disorders, cancer biology, and metabolic diseases. This research could be pivotal in delineating the molecular underpinnings of these conditions and identifying potential therapeutic targets.

In terms of scientific importance, these knockout cell lines serve as invaluable tools in both basic and translational research settings. They allow for the exploration of gene function in human cell contexts, facilitating drug discovery and development processes. Unlike alternative models such as overexpression systems or non-specific knockdown methodologies, the ZDHHC21 gene knockout cell lines provide a more precise means of elucidating gene function devoid of confounding effects, leading to improved experimental robustness.

This product is particularly compelling for researchers and clinicians who are focused on the cutting-edge fields of genomics and proteomics. The specificity and reliability of these cell lines make them ideal for high-throughput screening applications and functional assays, ultimately accelerating the pace of discovery in therapeutic interventions.

Our company prides itself on being at the forefront of cellular technology, ensuring high-quality, rigorously validated products that enrich scientific research endeavors. With our expertise in genetic engineering, we are committed to facilitating groundbreaking discoveries that can significantly impact health and disease management.

Please note that all services are for research use only. Not intended for any clinical use.

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