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ZDHHC16 Knockout Cell Lines

Gene: ZDHHC16

Official Full Name: zDHHC palmitoyltransferase 16provided by HGNC

Gene Summary: Enables palmitoyltransferase activity. Involved in protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24975 ZDHHC16 Knockout cell line (HeLa) Human ZDHHC16 1:3~1:6 Negative Online Inquiry
KO24976 ZDHHC16 Knockout cell line (HCT 116) Human ZDHHC16 1:2~1:4 Negative Online Inquiry
KO24977 ZDHHC16 Knockout cell line (HEK293) Human ZDHHC16 1:3~1:6 Negative Online Inquiry
KO24978 ZDHHC16 Knockout cell line (A549) Human ZDHHC16 1:3~1:4 Negative Online Inquiry

Background

ZDHHC16 Gene Knockout Cell Lines are engineered cellular systems in which the ZDHHC16 gene has been selectively disrupted, allowing for the study of its biological functions and implications in various cellular processes. This innovative product is a cornerstone for researchers aiming to unravel the complex roles of palmitoylation in signal transduction and membrane dynamics. ZDHHC16 encodes a protein involved in the palmitoylation of numerous substrates, impacting their localization, stability, and activity within cells.

The key mechanism behind these knockout cell lines involves the targeted editing of the ZDHHC16 gene through technologies such as CRISPR-Cas9 or homologous recombination, effectively abolishing the expression of the gene. Without ZDHHC16, researchers can investigate the downstream effects of disrupted palmitoylation pathways, offering insights into various diseases associated with aberrant lipid modifications, including neurological disorders and cancer. This makes the ZDHHC16 Gene Knockout Cell Lines invaluable tools for elucidating disease mechanisms and identifying potential therapeutic targets.

In research and clinical applications, these knockout cell lines facilitate high-throughput screenings, validation of drug targets, and the generation of disease models. Compared to alternative models, the ZDHHC16 knockout system provides a specific, reproducible, and controllable environment allowing for precise manipulation and observation of cellular responses.

These cell lines are particularly advantageous for researchers and clinicians striving for a deeper understanding of post-translational modifications and their implications in health and disease. By utilizing ZDHHC16 knockout cell lines, users can enhance their research initiatives, yielding more accurate data that drives innovation in therapeutic development.

Our company specializes in the production of high-quality, genetically modified cell lines and offers unparalleled expertise in gene editing technologies. With a commitment to advancing biological research, we provide essential tools that empower scientists and clinicians to accelerate their discoveries and improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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