Gene: ZDHHC13
Official Full Name: zDHHC palmitoyltransferase 13provided by HGNC
Gene Summary: Predicted to enable magnesium ion transmembrane transporter activity and protein-cysteine S-palmitoyltransferase activity. Involved in positive regulation of canonical NF-kappaB signal transduction. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00119 | ZDHHC13 Knockout cell line (293T) | Human | ZDHHC13 | 1:3~1:6 | Negative | Online Inquiry |
KO03601 | ZDHHC13 Knockout cell line (HeLa) | Human | ZDHHC13 | 1:3~1:6 | Negative | Online Inquiry |
KO03602 | ZDHHC13 Knockout cell line (HCT 116) | Human | ZDHHC13 | 1:2~1:4 | Negative | Online Inquiry |
KO03603 | ZDHHC13 Knockout cell line (HEK293) | Human | ZDHHC13 | 1:3~1:6 | Negative | Online Inquiry |
KO03604 | ZDHHC13 Knockout cell line (A549) | Human | ZDHHC13 | 1:3~1:4 | Negative | Online Inquiry |
ZDHHC13 Gene Knockout Cell Lines are specialized biological tools designed to facilitate the study of the ZDHHC13 gene, which encodes a palmitoyltransferase involved in the post-translational modification of proteins. By knocking out ZDHHC13, these cell lines allow researchers to investigate the gene's role in various cellular processes, including signal transduction, protein localization, and membrane dynamics. The mechanism underlying these cell lines involves targeted gene editing, typically leveraging CRISPR/Cas9 technology, resulting in a stable genetic alteration that provides insights into the functional consequences of ZDHHC13 loss.
The scientific importance of ZDHHC13 Gene Knockout Cell Lines lies in their applications across multiple domains of biomedical research. These include the investigation of neurodegenerative diseases, where dysregulation of protein palmitoylation has been implicated, as well as cancer biology, where cellular signaling pathways often become altered. By utilizing these cell lines, researchers can elucidate the specific roles of ZDHHC13 in various pathophysiological contexts, significantly contributing to the development of targeted therapeutic strategies.
Compared to alternative products, ZDHHC13 Gene Knockout Cell Lines offer unique advantages, including enhanced specificity and the ability to model conditions that closely mimic human disease states. Unlike conventional model systems, these knockout lines provide a more accurate representation of gene function, empowering researchers to make more reliable conclusions about the biological impact of ZDHHC13.
The value of ZDHHC13 Gene Knockout Cell Lines extends beyond basic research; they represent a critical resource for clinicians and biopharmaceutical companies focused on translational research and the development of new therapies. With these tools, the pathway to understanding and potentially manipulating cellular mechanisms has never been more accessible.
Our company specializes in high-quality genetic tools, ensuring that each ZDHHC13 Gene Knockout Cell Line is rigorously validated for performance and reliability. Our commitment to innovation and precision in biological research positions us as a leader in the field, dedicated to supporting scientists and clinicians in their pursuit of discovery and advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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