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ZC3H11B Knockout Cell Lines

Gene: ZC3H11B

Official Full Name: zinc finger CCCH-type containing 11Bprovided by HGNC

Gene Summary: Predicted to enable metal ion binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12469 ZC3H11B Knockout cell line (HCT 116) Human ZC3H11B 1:2~1:4 Negative Online Inquiry

Background

ZC3H11B Gene Knockout Cell Lines are genetically engineered cell lines in which the ZC3H11B gene has been inactivated or "knocked out," allowing researchers to study the gene's function and its role in various biological processes. ZC3H11B encodes a zinc finger protein believed to be involved in RNA processing, transcriptional regulation, and cellular signal transduction. By utilizing these knockout cell lines, scientists can explore the downstream effects of the absence of this gene on cellular behavior, phenotype, and disease models.

The primary function of the ZC3H11B Gene Knockout Cell Lines is to facilitate the investigation of gene-deletion effects. The mechanism relies on CRISPR/Cas9 technology, which precisely targets and disrupts specific genomic loci, leading to the loss of ZC3H11B expression. This genetic alteration allows for comparative studies with wild-type cell lines, enhancing understanding of gene function, potential compensatory mechanisms, and the gene’s contribution to cellular pathways and processes.

The scientific importance of these knockout cell lines extends to various domains, including cancer research, neurobiology, and other fields where understanding RNA metabolism and post-transcriptional regulation is vital. Application of these cells in experimental settings can yield insights into cancer cell proliferation, differentiation, and the impact of gene modulation on disease states, thereby providing valuable information for therapeutic strategies.

One of the specific advantages of our ZC3H11B Gene Knockout Cell Lines is their high efficiency and reliability. Compared to traditional knockout methods, such as homologous recombination, CRISPR/Cas9 yields faster results and greater specificity, significantly reducing off-target effects. Furthermore, these cell lines come well-characterized with detailed documentation of their successful gene knockout, providing assurance of experimental reproducibility.

For researchers and clinicians, these cell lines present a unique opportunity to advance understanding of complex biological systems and provide a foundation for innovative therapeutic approaches. The capacity to manipulate gene function in a controlled manner opens pathways for exploring pathological mechanisms and elucidating potential treatment targets.

Our company prides itself on its commitment to advancing scientific research by providing high-quality and innovative biological products. Our expertise in cutting-edge gene-editing technologies ensures that researchers receive trusted tools to propel their research forward, fostering breakthroughs in understanding and treating human diseases.

Please note that all services are for research use only. Not intended for any clinical use.

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