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ZBTB7B Knockout Cell Lines

Gene: ZBTB7B

Official Full Name: zinc finger and BTB domain containing 7Bprovided by HGNC

Gene Summary: This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23150 ZBTB7B Knockout cell line (HeLa) Human ZBTB7B 1:3~1:6 Negative Online Inquiry
KO23151 ZBTB7B Knockout cell line (HCT 116) Human ZBTB7B 1:2~1:4 Negative Online Inquiry
KO23152 ZBTB7B Knockout cell line (HEK293) Human ZBTB7B 1:3~1:6 Negative Online Inquiry
KO23153 ZBTB7B Knockout cell line (A549) Human ZBTB7B 1:3~1:4 Negative Online Inquiry

Background

ZBTB7B Gene Knockout Cell Lines are genetically modified cell lines specifically designed to study the role of the ZBTB7B gene, also known as the POZ/BTB domain containing zinc finger protein 7, in various biological processes. These cell lines have been created using precise gene editing techniques, such as CRISPR/Cas9, to effectively knock out the functional expression of the ZBTB7B gene, allowing researchers to investigate the gene's contributions to cellular functions, gene regulation, and its potential role in disease mechanisms.

The key functions of ZBTB7B involve regulatory control over various signaling pathways and transcriptional activities, influencing processes such as cell proliferation, differentiation, and immune responses. By utilizing knockout cell lines, researchers can elucidate the molecular mechanisms through which ZBTB7B exerts its effects, providing insights that are crucial for understanding its involvement in pathologies including cancer and autoimmune disorders.

The scientific importance of ZBTB7B Gene Knockout Cell Lines extends into both research and clinical settings. These cell lines serve as powerful tools for investigating gene function and gene-targeted therapies, as well as facilitating drug discovery and testing. Furthermore, their use allows for the development of more effective therapeutic strategies by unveiling novel therapeutic targets linked to the ZBTB7B gene.

Compared to existing alternatives, such as traditional RNA interference or transgenic models, the ZBTB7B Gene Knockout Cell Lines offer enhanced precision and stability in gene expression manipulation. This precision minimizes off-target effects, which are characteristic of RNA-based strategies, and provides clearer insights into gene function. The ability to create stable knockout models means researchers can achieve reproducibility in their experiments, a critical factor in study validation.

The value of ZBTB7B Gene Knockout Cell Lines lies in their capacity to empower researchers and clinicians with a deeper understanding of gene function and its role in disease. This knowledge not only enhances basic biological research but also drives innovation in therapeutic development and precision medicine approaches.

Our company specializes in the production of high-quality genetic materials and cell lines, leveraging advanced biotechnologies to cater to the specific needs of the scientific community. By offering ZBTB7B Gene Knockout Cell Lines, we aim to support breakthrough research and elevate the field of molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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