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ZBTB49 Knockout Cell Lines

Gene: ZBTB49

Official Full Name: zinc finger and BTB domain containing 49provided by HGNC

Gene Summary: Enables DNA-binding transcription factor binding activity; sequence-specific DNA binding activity; and transcription coactivator binding activity. Involved in negative regulation of cell population proliferation; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle. Located in cytosol; microtubule cytoskeleton; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12474 ZBTB49 Knockout cell line (HeLa) Human ZBTB49 1:3~1:6 Negative Online Inquiry
KO12475 ZBTB49 Knockout cell line (HCT 116) Human ZBTB49 1:2~1:4 Negative Online Inquiry
KO12476 ZBTB49 Knockout cell line (HEK293) Human ZBTB49 1:3~1:6 Negative Online Inquiry
KO12477 ZBTB49 Knockout cell line (A549) Human ZBTB49 1:3~1:4 Negative Online Inquiry

Background

ZBTB49 Gene Knockout Cell Lines are genetically modified cell lines where the ZBTB49 gene has been inactivated, providing a powerful tool for the investigation of gene function and cellular processes. ZBTB49, known for its role in transcription regulation, is implicated in various biological functions, including immune response, cellular differentiation, and apoptosis. By utilizing these knockout cell lines, researchers can elucidate the specific pathways and mechanisms influenced by ZBTB49, facilitating a deeper understanding of its contributions to disease models and therapeutic targets.

The key mechanism of action involves the disruption of the ZBTB49 gene, achieved through CRISPR-Cas9 technology or similar gene-editing techniques. This targeted approach results in a complete loss of ZBTB49 expression, enabling scientists to assess changes in cellular behavior compared to wild-type cell lines. Consequently, the ZBTB49 knockout models serve as invaluable resources for studying gene function in contexts such as cancer biology, immunology, and developmental biology.

The scientific importance of ZBTB49 Gene Knockout Cell Lines is underscored by their diverse applications in both research and clinical settings. They offer insights into the role of ZBTB49 in disease mechanisms, opening avenues for novel diagnostics and targeted therapies. Moreover, the ability to mimic various pathological conditions using these knockout models enhances translational research, leading to more effective treatment strategies.

Compared to traditional knockout methods or knockdown strategies, our ZBTB49 Gene Knockout Cell Lines provide a more stable and robust genetic modification, ensuring that researchers can confidently reproduce experiments. This reliability, coupled with the cell lines' versatility across different experimental setups, positions them as essential assets in any molecular biology or genetics laboratory.

For researchers and clinicians seeking to advance their understanding of gene function and its implications in health and disease, ZBTB49 Gene Knockout Cell Lines offer formidable advantages. They empower users to explore gene-pathway interactions under carefully controlled conditions, leading to impactful discoveries.

With extensive expertise in genetic engineering and cell line development, our company delivers high-quality biological products that meet rigorous scientific standards. Trust our commitment to advancing scientific research with innovative solutions like the ZBTB49 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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