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ZBTB48 Knockout Cell Lines

Gene: ZBTB48

Official Full Name: zinc finger and BTB domain containing 48provided by HGNC

Gene Summary: Enables double-stranded telomeric DNA binding activity; identical protein binding activity; and transcription cis-regulatory region binding activity. Involved in positive regulation of DNA-templated transcription and telomere maintenance via telomere lengthening. Located in chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37376 ZBTB48 Knockout cell line (HeLa) Human ZBTB48 1:3~1:6 Negative Online Inquiry
KO37377 ZBTB48 Knockout cell line (HCT 116) Human ZBTB48 1:2~1:4 Negative Online Inquiry
KO37378 ZBTB48 Knockout cell line (HEK293) Human ZBTB48 1:3~1:6 Negative Online Inquiry
KO37379 ZBTB48 Knockout cell line (A549) Human ZBTB48 1:3~1:4 Negative Online Inquiry

Background

ZBTB48 Gene Knockout Cell Lines are specialized cellular models that have been engineered to lack the expression of the ZBTB48 gene, which encodes a zinc finger protein involved in various regulatory functions within the cell. This approach utilizes CRISPR/Cas9 gene-editing technology to facilitate precise modifications in targeted organisms, thereby allowing researchers to elucidate the gene's role in cellular mechanisms and pathways.

The primary function of ZBTB48 is as a transcriptional regulator, influencing a range of biological processes, including cell proliferation, differentiation, and immune responses. By studying ZBTB48 knockout cell lines, researchers can examine alterations in gene expression profiles, signaling pathways, and cellular behavior that occur in the absence of this gene. This exploration is vital for understanding not only basic biological functions but also the implications in diseases such as cancer, autoimmune disorders, and neurodegenerative diseases.

In research and clinical settings, ZBTB48 knockout cell lines serve as invaluable tools for functional genomics, drug discovery, and therapeutic development. They allow scientists to identify downstream targets, assess phenotypic changes, and test the efficacy of novel compounds in a controlled environment, ultimately leading to groundbreaking discoveries that can pave the way for new treatments.

Unlike traditional knockout models, ZBTB48 gene knockout cell lines offer enhanced specificity, improved reproducibility, and reduced time in experimental procedures. The ability to quickly generate these cell lines using CRISPR technology ensures that researchers have immediate access to precise models suited for their studies.

Researchers and clinicians looking to deepen their insight into gene function will find ZBTB48 gene knockout cell lines to be a robust and adaptable resource. With these specialized models, key biological questions can be addressed with a high degree of confidence, offering clarity in complex biological landscapes.

Our company specializes in the development and provision of high-quality biological products, ensuring that researchers have the tools they need to advance their work effectively. With a commitment to precision and innovation, we empower the scientific community to make significant strides in research and therapeutics.

Please note that all services are for research use only. Not intended for any clinical use.

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