Gene: WIPF3
Official Full Name: WAS/WASL interacting protein family member 3provided by HGNC
Gene Summary: Predicted to enable alpha-tubulin binding activity and gamma-tubulin binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation; endosomal transport; and exocytosis. Predicted to be located in cytosol. Predicted to be part of WASH complex. Predicted to be active in early endosome; recycling endosome; and synapse. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12598 | WIPF3 Knockout cell line (HCT 116) | Human | WIPF3 | 1:2~1:4 | Negative | Online Inquiry |
KO12599 | WIPF3 Knockout cell line (HEK293) | Human | WIPF3 | 1:3~1:6 | Negative | Online Inquiry |
WIPF3 Gene Knockout Cell Lines are advanced biological models engineered to facilitate the study of the WIPF3 gene function and its implications in various cellular processes. These cell lines are created through CRISPR-Cas9 technology, allowing for precise and efficient gene knockout, resulting in a complete absence of WIPF3 protein expression. By eliminating this critical component, researchers can investigate the downstream effects on cellular pathways, protein interactions, and overall cell behavior, paving the way for a deeper understanding of the gene's role in health and disease.
The primary function of WIPF3 Gene Knockout Cell Lines lies in their ability to serve as a robust platform for functional genomics studies. The absence of WIPF3 allows researchers to elucidate its involvement in immune responses, cytoskeletal dynamics, and potential oncogenic processes. Such insights are particularly valuable for deciphering the molecular mechanisms underlying various pathologies, including cancer and autoimmune disorders.
In both research and clinical contexts, these cell lines offer several advantages over traditional knockout models. They provide reproducibility and ease of use, critical for high-throughput screening applications. Moreover, the precision of CRISPR technology minimizes off-target effects, ensuring that the observed phenotypes are directly attributable to WIPF3 loss.
These unique attributes position WIPF3 Gene Knockout Cell Lines as an invaluable tool for researchers seeking to explore gene function and regulatory networks. Their application can enhance drug discovery efforts and foster the development of novel therapeutic approaches targeting WIPF3-related pathologies.
With our deep expertise in genetic engineering and a commitment to advancing biological research, our company excels in providing high-quality, customized cell lines that empower researchers and clinicians to achieve groundbreaking discoveries in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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