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WIPF2 Knockout Cell Lines

Gene: WIPF2

Official Full Name: WAS/WASL interacting protein family member 2provided by HGNC

Gene Summary: This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23835 WIPF2 Knockout cell line (HeLa) Human WIPF2 1:3~1:6 Negative Online Inquiry
KO23836 WIPF2 Knockout cell line (HCT 116) Human WIPF2 1:2~1:4 Negative Online Inquiry
KO23837 WIPF2 Knockout cell line (HEK293) Human WIPF2 1:3~1:6 Negative Online Inquiry
KO23838 WIPF2 Knockout cell line (A549) Human WIPF2 1:3~1:4 Negative Online Inquiry

Background

WIPF2 Gene Knockout Cell Lines are specialized cellular models designed to investigate the functional role of the WIPF2 gene, which encodes a protein involved in cytoskeletal dynamics and cellular signaling pathways. These cell lines are generated through precision genome editing techniques, such as CRISPR/Cas9, resulting in the complete knockout of WIPF2 expression. By effectively disrupting the gene's function, researchers can elucidate the precise biological mechanisms influenced by WIPF2 and its implications in various physiological processes as well as disease states.

The primary mechanisms through which WIPF2 knockout cell lines operate include the alteration of cellular morphology, migration patterns, and signaling cascades that are essential for numerous cellular functions. Researchers can utilize these models to explore the gene's involvement in actin filament organization, endocytosis, and the modulation of cellular responses to external stimuli. Such insights are crucial for understanding diseases characterized by dysregulated cellular dynamics, including cancer progression and neurodegeneration.

In both research and clinical settings, WIPF2 Gene Knockout Cell Lines serve as a critical tool for identifying therapeutic targets and biomarkers. The unique ability to directly observe the effects of WIPF2 loss makes these models indispensable for drug discovery and validation processes, paving the way for the development of novel interventions.

Compared to alternative models, such as transient knockdown approaches, WIPF2 knockout cell lines provide a more stable and reproducible system for assessing the long-term effects of WIPF2 loss, thus enhancing the reliability of experimental outcomes. Their application in various cell types allows for versatile experimental designs tailored to specific research questions.

For researchers and clinicians alike, the value of WIPF2 Gene Knockout Cell Lines lies in their contributions to advancing our understanding of gene function, disease mechanisms, and potential therapeutic strategies. Our company prides itself on delivering high-quality biological products, backed by years of expertise in genetic engineering and cell line development, ensuring that our customers have the tools they need to make groundbreaking discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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