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WASHC2A Knockout Cell Lines

Gene: WASHC2A

Official Full Name: WASH complex subunit 2Aprovided by HGNC

Gene Summary: Predicted to enable phosphatidylinositol phosphate binding activity and retromer complex binding activity. Involved in protein localization to endosome. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12630 WASHC2A Knockout cell line (HeLa) Human WASHC2A 1:3~1:6 Negative Online Inquiry
KO12631 WASHC2A Knockout cell line (HCT 116) Human WASHC2A 1:2~1:4 Negative Online Inquiry
KO12632 WASHC2A Knockout cell line (HEK293) Human WASHC2A 1:3~1:6 Negative Online Inquiry
KO12633 WASHC2A Knockout cell line (A549) Human WASHC2A 1:3~1:4 Negative Online Inquiry

Background

WASHC2A Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the WASHC2A gene, a component of the Wiskott-Aldrich Syndrome Protein and SCAR homology (WASH) complex, which plays a critical role in endosomal sorting and actin polymerization. By knocking out the WASHC2A gene, these cell lines allow researchers to investigate the functional implications of this gene's absence, providing insights into various biological processes such as vesicle trafficking, cell motility, and immune responses.

The key functionality of WASHC2A Gene Knockout Cell Lines lies in their ability to mimic a loss-of-function scenario for the WASHC2A protein, enabling researchers to explore downstream effects and compensatory mechanisms in cell biology. The knockout model can be utilized to assess changes in cellular morphology, dynamics of endocytosis, and overall cellular behaviors that are crucial for understanding diseases related to immune function and cancer.

Scientifically, WASHC2A Gene Knockout Cell Lines are invaluable in basic research and translational studies. Their applications extend to cancer biology, therapeutic development, and studies of immunological disorders. By elucidating the role of WASHC2A in pathogenic processes, researchers can develop targeted strategies for intervention and therapy, opening pathways to innovative treatment options.

Compared to alternative models that may not fully represent the functional consequences of gene mutations or deletions, these knockout cell lines provide a more accurate depiction of biological events. The specific loss of the WASHC2A function allows for straightforward comparisons and assessments, improving the reliability of experimental results.

For researchers and clinicians, the value of WASHC2A Gene Knockout Cell Lines is evident in their capacity to deepen the understanding of complex molecular mechanisms and disease states. By leveraging such powerful tools, scientists can refine hypotheses, validate targets for drug development, and enhance the reproducibility of their work.

Our company has a proven track record in producing high-quality biological products, supported by extensive expertise in genetic engineering and cell line development. We are committed to advancing research capabilities with innovative solutions that foster discoveries in cellular and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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