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VTI1B Knockout Cell Lines

Gene: VTI1B

Official Full Name: vesicle transport through interaction with t-SNAREs 1Bprovided by HGNC

Gene Summary: Enables SNARE binding activity and chloride channel inhibitor activity. Involved in regulation of protein localization to plasma membrane. Located in several cellular components, including endosome membrane; lysosomal membrane; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31820 VTI1B Knockout cell line (HeLa) Human VTI1B 1:3~1:6 Negative Online Inquiry
KO31821 VTI1B Knockout cell line (HCT 116) Human VTI1B 1:2~1:4 Negative Online Inquiry
KO31822 VTI1B Knockout cell line (HEK293) Human VTI1B 1:3~1:6 Negative Online Inquiry
KO31823 VTI1B Knockout cell line (A549) Human VTI1B 1:3~1:4 Negative Online Inquiry

Background

VTI1B Gene Knockout Cell Lines are specialized cell models characterized by the targeted disruption of the VTI1B gene, which plays a crucial role in membrane trafficking and vesicular transport processes. By leveraging CRISPR-Cas9 technology, these cell lines provide valuable tools for studying the physiological and pathological roles of VTI1B and its interactions within various cellular contexts. The knockout of this gene allows researchers to observe phenotypic changes and molecular pathways that are otherwise masked in wild-type cell lines, thereby enabling a deeper understanding of cellular mechanisms.

The primary functions of VTI1B relate to its involvement in synaptic vesicle trafficking and exocytotic processes, with implications for neurobiology and hormone secretion. Through gene knockout, researchers can investigate alterations in secretion pathways, synaptic function, and neuronal communication, making these cell lines particularly pertinent in studies of neurodegenerative diseases and metabolic disorders. This strategic model assists in elucidating the underlying mechanisms that may contribute to a broader range of medical conditions.

The scientific importance of VTI1B Gene Knockout Cell Lines extends to their application in drug discovery and therapeutic development. By utilizing these models, researchers can test the efficacy and specificity of novel compounds aimed at targeting VTI1B-related pathways, thereby facilitating the identification of potential clinical drug candidates. Furthermore, such insights can inform gene therapy approaches, providing a foundation for innovative treatments.

What sets VTI1B Gene Knockout Cell Lines apart from alternative models is their high specificity and reliability, coupled with rigorous validation processes that ensure consistent performance in experimental setups. This reliability significantly enhances experimental reproducibility and data integrity, which are critical in scientific research.

For researchers and clinicians, investing in VTI1B Gene Knockout Cell Lines means access to a state-of-the-art platform for groundbreaking discoveries. The professional oversight from our team's expertise in genetic engineering and cell biology further guarantees that users will receive not only a product but a partnership in advancing their research goals. This commitment to quality and innovation underscores our dedication to supporting the scientific community with industry-leading biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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