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VPS13B Knockout Cell Lines

Gene: VPS13B

Official Full Name: vacuolar protein sorting 13 homolog Bprovided by HGNC

Gene Summary: This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12670 VPS13B Knockout cell line (HeLa) Human VPS13B 1:3~1:6 Negative Online Inquiry
KO12671 VPS13B Knockout cell line (HCT 116) Human VPS13B 1:2~1:4 Negative Online Inquiry
KO12672 VPS13B Knockout cell line (HEK293) Human VPS13B 1:3~1:6 Negative Online Inquiry
KO12673 VPS13B Knockout cell line (A549) Human VPS13B 1:3~1:4 Negative Online Inquiry

Background

VPS13B Gene Knockout Cell Lines represent a pivotal advancement in the field of genetic research, specifically focusing on the VPS13B gene, which is implicated in neurological disorders such as Chorea-Acanthocytosis. These specialized cell lines are meticulously engineered to lack the functional VPS13B gene, providing researchers with invaluable models to study the gene's role in cellular functions and disease mechanisms.

The primary function of these knockouts is to facilitate the exploration of VPS13B's contributions to membrane trafficking, lipid metabolism, and neuronal health. Through the removal of this gene, researchers can investigate how its absence alters cellular behaviors, gene expression profiles, and molecular pathways implicated in pathology. This mechanism offers a clearer understanding of the underlying biological processes and potential compensatory mechanisms activated in cells.

In scientific research and clinical settings, VPS13B Gene Knockout Cell Lines are crucial for elucidating the pathophysiology of related disorders, enabling the development of therapeutic interventions and targeted gene therapies. Their application spans from basic research to translational science, fostering collaborations between molecular biologists, geneticists, and pharmacologists.

What sets our VPS13B Gene Knockout Cell Lines apart is their high fidelity and reproducibility, backed by rigorous quality controls. Unlike alternative models that may not fully replicate the gene's loss, these lines provide a comprehensive representation of VPS13B knockout scenarios, ensuring consistent and meaningful data collection.

For researchers and clinicians, these cell lines offer unique insights into neurodegenerative disease mechanisms, making them invaluable tools for advancing our understanding and development of innovative therapies. By investing in our VPS13B Gene Knockout Cell Lines, users can leverage our company’s deep expertise in genetic engineering and commitment to producing high-quality biological products, making a significant impact in their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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