Gene: VGF
Official Full Name: VGF nerve growth factor inducibleprovided by HGNC
Gene Summary: This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34827 | VGF Knockout cell line (HCT 116) | Human | VGF | 1:2~1:4 | Negative | Online Inquiry |
KO34828 | VGF Knockout cell line (HEK293) | Human | VGF | 1:3~1:6 | Negative | Online Inquiry |
VGF Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted genome editing to delete the VGF gene, which encodes a neuropeptide implicated in various physiological processes, including energy balance, neurogenesis, and adaptive responses to stress. These cell lines are invaluable tools for researchers investigating the role of VGF in cellular signaling, neuronal function, and metabolic disorders.
The key function of VGF Gene Knockout Cell Lines lies in their utility for elucidating the specific pathways and biological mechanisms regulated by the VGF protein. By providing a precise model to study the absence of this neuropeptide, researchers can observe resultant changes in cellular behavior, such as altered signaling pathways and modifications in gene expression. The knockout model enables researchers to dissect out the physiological implications of VGF deletion, facilitating advancements in understanding diseases linked to this gene, such as obesity, diabetes, and depression.
The scientific importance of VGF Gene Knockout Cell Lines is underscored by their diverse applications in both basic and applied research settings. They can serve as critical platforms for drug discovery, neurobiological studies, and genetic investigations aimed at developing targeted therapies. Discovering the functions of VGF may lead to novel therapeutic strategies for metabolic and neurodegenerative diseases, making these cell lines exceedingly valuable for both academic and clinical research institutions.
What sets VGF Gene Knockout Cell Lines apart from alternative models is their specific focus on the VGF gene and the precision of the knockout technology employed. This specificity allows for a deeper understanding of VGF's role without the confounding factors that may arise from partial gene expression or functional redundancy that can occur in wild-type models. Furthermore, these cell lines are robust, reproducible, and compatible with a variety of research methodologies, including CRISPR/Cas9 gene editing, transcriptomic analyses, and metabolic assays.
Investing in VGF Gene Knockout Cell Lines represents a significant opportunity for researchers and clinicians seeking to advance their understanding of complex biological systems. By leveraging this advanced model, users can accelerate their research timelines while driving innovative solutions in clinical applications. Our company's expertise in gene editing and cellular biology ensures that our products are at the forefront of scientific discovery, equipping researchers with the necessary tools to explore cellular functions with precision and clarity.
Please note that all services are for research use only. Not intended for any clinical use.
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