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USP9X Knockout Cell Lines

Gene: USP9X

Official Full Name: ubiquitin specific peptidase 9 X-linkedprovided by HGNC

Gene Summary: This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02786 USP9X Knockout cell line (HeLa) Human USP9X 1:3~1:6 Negative Online Inquiry
KO02787 USP9X Knockout cell line (HCT 116) Human USP9X 1:2~1:4 Negative Online Inquiry
KO02788 USP9X Knockout cell line (HEK293) Human USP9X 1:3~1:6 Negative Online Inquiry
KO02789 USP9X Knockout cell line (A549) Human USP9X 1:3~1:4 Negative Online Inquiry

Background

USP9X Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the ubiquitin-specific protease 9X (USP9X) gene's functions and its associated pathways. These cell lines have been engineered to exhibit a complete loss of USP9X expression, providing a unique platform for researchers to explore the gene's role in cellular processes such as protein degradation, cell signaling, and the regulation of various physiological functions. USP9X is known to be involved in the deubiquitination process, influencing protein stability and turnover, making these knockout models crucial for dissecting the biological mechanisms underlying diseases, including cancer and neurodegeneration.

The key function of USP9X Gene Knockout Cell Lines lies in their ability to reveal the consequences of USP9X loss on cellular behavior and molecular dynamics. By employing CRISPR-Cas9 technology to achieve precise gene editing, these cell lines provide a controlled environment for investigating USP9X’s role in maintaining cellular homeostasis and its interaction with other signaling pathways. Researchers can leverage these models to elucidate the gene’s impact on cellular stress responses, apoptosis, and developmental processes, advancing our understanding of its potential as a therapeutic target.

The scientific importance of these cell lines cannot be understated; they serve as invaluable tools in both academic and clinical research settings, particularly for elucidating the complex roles of deubiquitinating enzymes. Unlike traditional methods of studying gene functions, which may lack specificity and reproducibility, USP9X Gene Knockout Cell Lines allow for the direct assessment of phenotypic changes in controlled experiments, leading to more reliable and interpretable results.

One of the distinct advantages of USP9X Gene Knockout Cell Lines over alternatives is their high specificity and efficiency in gene disruption. Researchers can confidently draw parallels between the findings in these cell lines and in vivo systems, thus increasing the translational potential of their studies. Additionally, the availability of these knockout models reduces reliance on complex genetic manipulation methods, simplifies experimental designs, and accelerates discovery timelines.

This product represents a vital advancement for researchers seeking to deepen their understanding of USP9X and its associated pathways. By utilizing USP9X Gene Knockout Cell Lines, scientists can champion innovative solutions to pressing biomedical challenges. Our company, with its commitment to delivering high-quality biological tools, possesses extensive expertise in genetic engineering and cell line development, and we aim to empower researchers with the resources they need to drive impactful scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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