Gene: USP24
Official Full Name: ubiquitin specific peptidase 24provided by HGNC
Gene Summary: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29385 | USP24 Knockout cell line (HeLa) | Human | USP24 | 1:3~1:6 | Negative | Online Inquiry |
KO29386 | USP24 Knockout cell line (HCT 116) | Human | USP24 | 1:2~1:4 | Negative | Online Inquiry |
KO29387 | USP24 Knockout cell line (HEK293) | Human | USP24 | 1:3~1:6 | Negative | Online Inquiry |
KO29388 | USP24 Knockout cell line (A549) | Human | USP24 | 1:3~1:4 | Negative | Online Inquiry |
USP24 Gene Knockout Cell Lines are specialized biological tools that involve the targeted deletion of the USP24 gene, which is integral in regulating cellular processes such as the ubiquitin-proteasome system, DNA repair, and cell cycle control. These knockout cell lines are generated using advanced CRISPR/Cas9 technology, ensuring precise modification of the DNA sequence, leading to a loss of function that allows researchers to study the gene's role in various physiological and pathological contexts.
The primary function of USP24 Gene Knockout Cell Lines is to provide a reliable model for examining the implications of USP24 in cellular homeostasis and disease mechanisms. By disrupting the USP24 gene, these cell lines facilitate insight into how its absence affects cellular processes like tumorigenesis, signaling pathways, and response to stress. Additionally, using these cell lines, researchers can evaluate potential therapeutic targets and drug efficacy, providing a strong platform for translational research in oncology and beyond.
In scientific research and clinical settings, understanding the function of USP24 is crucial, as its dysregulation is linked to various diseases, including cancer and neurodegenerative disorders. Consequently, with these knockout cell lines, scientists can dissect the mechanisms underlying these conditions and explore novel treatment strategies. The USP24 Gene Knockout Cell Lines stand out from alternative models due to their precise germline alterations, which can improve reproducibility and experimental accuracy, significantly enhancing the quality of research outcomes.
Researchers and clinicians will find immense value in employing USP24 Gene Knockout Cell Lines, as they offer a cutting-edge approach to understanding the complexity of gene function in disease. The reliable and reproducible nature of these cell lines sets them apart, paving the way for innovative breakthroughs in therapeutic development.
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Please note that all services are for research use only. Not intended for any clinical use.
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