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USF3 Knockout Cell Lines

Gene: USF3

Official Full Name: upstream transcription factor family member 3provided by HGNC

Gene Summary: This gene encodes a large protein that contains a helix-loop-helix domain and a polyglutamine region. A deletion in the polyglutamine region was associated with risk for thyroid carcinoma. [provided by RefSeq, May 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34192 USF3 Knockout cell line (HeLa) Human USF3 1:3~1:6 Negative Online Inquiry
KO34193 USF3 Knockout cell line (HCT 116) Human USF3 1:2~1:4 Negative Online Inquiry
KO34194 USF3 Knockout cell line (HEK293) Human USF3 1:3~1:6 Negative Online Inquiry
KO34195 USF3 Knockout cell line (A549) Human USF3 1:3~1:4 Negative Online Inquiry

Background

USF3 Gene Knockout Cell Lines are specially engineered cellular models in which the USF3 gene has been disrupted, allowing researchers to study the gene's functional role in various biological processes. These cell lines provide a powerful tool for investigating the implications of USF3 deficiency, which has been linked to crucial pathways in cellular signaling, metabolism, and developmental biology.

The key mechanism behind these knockout cell lines lies in precise genome editing techniques, such as CRISPR/Cas9 or TALENs, employed to selectively deactivate the USF3 gene. This loss-of-function approach enables scientists to dissect the molecular pathways affected when USF3 is absent, providing insights into its role in transcriptional regulation, protein interactions, and cellular responses to environmental stresses. By utilizing these cell lines, researchers can create a clearer picture of the gene's impact on cellular behavior, contributing to both fundamental biological understanding and potential therapeutic strategies.

The scientific importance of USF3 Gene Knockout Cell Lines extends to diverse research areas, including cancer biology, metabolic disorders, and developmental studies. In clinical settings, such models can assist in the identification of novel drug targets, allowing for more effective therapeutic interventions aimed at conditions linked to USF3 dysregulation.

Compared to traditional models, such as wild-type or overexpression systems, USF3 Gene Knockout Cell Lines offer enhanced specificity and reliability in the study of gene function. Researchers benefit from a straightforward, reproducible platform that eliminates the confounding effects seen in other methodologies, enabling cleaner experimental outcomes and robust data.

For researchers and clinicians pursuing state-of-the-art insights into gene function and mechanism, the USF3 Gene Knockout Cell Lines represent a valuable addition to their experimental toolkit. Our company prides itself on its commitment to advancing scientific research through innovative biological products, ensuring our clients have access to high-quality tools that facilitate groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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