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UQCC2 Knockout Cell Lines

Gene: UQCC2

Official Full Name: ubiquinol-cytochrome c reductase complex assembly factor 2provided by HGNC

Gene Summary: This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. [provided by RefSeq, Oct 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03967 UQCC2 Knockout cell line (HeLa) Human UQCC2 1:3~1:6 Negative Online Inquiry
KO03968 UQCC2 Knockout cell line (HCT 116) Human UQCC2 1:2~1:4 Negative Online Inquiry
KO03969 UQCC2 Knockout cell line (HEK293) Human UQCC2 1:3~1:6 Negative Online Inquiry
KO03970 UQCC2 Knockout cell line (A549) Human UQCC2 1:3~1:4 Negative Online Inquiry

Background

UQCC2 Gene Knockout Cell Lines represent a groundbreaking tool for studying the role of the UQCC2 gene in various biological processes and diseases. These cell lines are genetically engineered to disrupt the expression of the UQCC2 gene, enabling researchers to dissect its functions in cellular pathways and assess its contributions to physiological and pathological states. By utilizing CRISPR-Cas9 technology, these cell lines provide a precise and efficient method for gene knockout, allowing for greater specificity in experimental designs.

The key functionality of UQCC2 Knockout Cell Lines lies in their ability to serve as a foundational platform for investigating mitochondrial function and its implications in cellular metabolism, apoptosis, and various diseases, including cancer and neurodegenerative disorders. The knockout of UQCC2 can elucidate its role in processes such as protein sorting within mitochondria, highlighting its importance in mitochondrial homeostasis. This understanding is critical for researchers attempting to explore therapeutic avenues targeting mitochondrial dysfunction.

In scientific settings, these cell lines are invaluable for drug screening, genetic studies, and functional assays, facilitating enhanced insights into disease mechanisms. Their unique capacity to model specific genetic environments allows researchers to explore the effects of UQCC2 loss in cellular behavior, significantly contributing to the understanding of disease pathology.

Compared to traditional methods of gene knockout that can be time-consuming and less efficient, the UQCC2 Gene Knockout Cell Lines offer researchers a streamlined approach to gene manipulation, reducing the time and costs associated with cell line development. The precision afforded by the CRISPR technology further ensures high targeting efficacy and reproducibility.

For researchers and clinicians focused on mitochondrial biology and disease mechanisms, these cell lines present a value proposition that cannot be overlooked. They not only provide a robust platform for hypothesis-driven research but also foster the development of targeted therapies aimed at diseases linked to UQCC2 functionality.

As a company with extensive expertise in developing cutting-edge biological research tools, we take pride in offering these UQCC2 Gene Knockout Cell Lines, supporting the scientific community in advancing our collective understanding of complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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