Gene: UNC5A
Official Full Name: unc-5 netrin receptor Aprovided by HGNC
Gene Summary: UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM, Apr 2004]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23809 | UNC5A Knockout cell line (HCT 116) | Human | UNC5A | 1:2~1:4 | Negative | Online Inquiry |
UNC5A Gene Knockout Cell Lines are genetically engineered cell models specifically designed to lack the UNC5A gene, a critical component involved in various physiological processes including neural development and apoptosis. These cell lines serve as vital tools for researchers studying the mechanisms of cell signaling, neurobiology, and cancer biology.
The primary function of UNC5A gene knockout cell lines is to elucidate the role of the UNC5A protein in cellular responses. By creating a controlled environment where the gene is silenced, researchers can investigate downstream signaling pathways and understand how its absence affects cellular behavior. Knockout technology typically involves CRISPR/Cas9 or TALEN methods, allowing precise edits to the genome, which facilitate the study of phenotypic changes such as altered migration, differentiation, or response to stimuli.
From a scientific perspective, UNC5A knockouts hold significant importance, particularly in research applications focused on neurodegenerative diseases, where this gene is implicated in neuronal survival and death. Additionally, the insights gained from studying these cell lines have potential therapeutic implications, especially in designing targeted therapies that modulate UNC5A-related pathways.
One of the unique advantages of using UNC5A Gene Knockout Cell Lines is their precision. Unlike alternative models that may include multiple genetic variables, these knockout lines provide specificity in experimental designs, limiting confounding factors. Furthermore, they facilitate high-throughput screening processes, allowing researchers to identify potential drug targets efficiently.
For researchers and clinicians, the value of UNC5A Gene Knockout Cell Lines is evident in their ability to provide clarity in understanding gene function and disease mechanisms. This translates into more informed hypotheses and experimental designs, ultimately advancing scientific knowledge and therapeutic strategies.
Our company is committed to providing high-quality biological products backed by rigorous scientific research, ensuring that our UNC5A Gene Knockout Cell Lines are not only reliable but also tailored to meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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