Gene: UHMK1
Official Full Name: U2AF homology motif kinase 1provided by HGNC
Gene Summary: The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06024 | UHMK1 Knockout cell line (HeLa) | Human | UHMK1 | 1:3~1:6 | Negative | Online Inquiry |
KO06025 | UHMK1 Knockout cell line (HCT 116) | Human | UHMK1 | 1:2~1:4 | Negative | Online Inquiry |
KO06026 | UHMK1 Knockout cell line (HEK293) | Human | UHMK1 | 1:3~1:6 | Negative | Online Inquiry |
KO06027 | UHMK1 Knockout cell line (A549) | Human | UHMK1 | 1:3~1:4 | Negative | Online Inquiry |
UHMK1 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of UHMK1 (Ubiquitin-like Modifier Activating Kinase 1), a crucial gene involved in numerous cellular processes, including stress responses, cell cycle regulation, and differentiation. These knockout cell lines have been engineered to selectively deactivate the UHMK1 gene, allowing researchers to investigate the functional consequences of its absence, elucidating the gene's role in various biological pathways and diseases.
The primary function of these knockout cell lines is to provide a stable environment for researchers to observe the effects of UHMK1 deletion on cellular physiology. This is achieved through CRISPR-Cas9 technology, which allows for precise genomic editing. As a result, these cell lines serve as an invaluable tool for understanding the gene’s role in oncogenesis, neurodegenerative diseases, and metabolic disorders. By comparing the knockout lines to wild-type counterparts, researchers can robustly assess changes in gene expression, signaling pathways, and phenotypic traits.
The scientific importance of UHMK1 Gene Knockout Cell Lines is further underscored by their applications in both research and clinical settings. They are instrumental in drug discovery, where identifying potential inhibitors or modulators of UHMK1 may lead to novel therapeutic approaches. Additionally, they can be utilized to explore the gene's implications in human diseases, offering insights into mechanisms that could be targeted for clinical intervention.
What sets UHMK1 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Unlike general knockout models that may result in off-target effects, these cell lines are validated for accuracy, ensuring that results are attributable solely to UHMK1 disruption. Furthermore, they come with comprehensive data and support, making it easier for researchers to incorporate them into their studies.
For researchers and clinicians seeking to advance their understanding of UHMK1 and its biological significance, these knockout cell lines offer a critical resource that bridges basic research and therapeutic application. Investing in UHMK1 Gene Knockout Cell Lines means leveraging cutting-edge technology and conducting experiments with a high degree of confidence in the data collected.
Our company is committed to providing high-quality biological products backed by rigorous scientific standards, ensuring that our clients have access to the tools necessary for groundbreaking research and innovation in the field of molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.