Gene: UFSP2
Official Full Name: UFM1 specific peptidase 2provided by HGNC
Gene Summary: This gene encodes a highly conserved cysteine protease. The protein cleaves two C-terminal residues from ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein. Activation of ubiquitin-fold modifier 1 by the encoded protein exposes a C-terminal glycine residue that allows interaction with other proteins and transfer to its target protein. An allelic variant of this gene has been associated with Beukes hip dysplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12827 | UFSP2 Knockout cell line (HeLa) | Human | UFSP2 | 1:3~1:6 | Negative | Online Inquiry |
KO12828 | UFSP2 Knockout cell line (HCT 116) | Human | UFSP2 | 1:2~1:4 | Negative | Online Inquiry |
KO12829 | UFSP2 Knockout cell line (HEK293) | Human | UFSP2 | 1:3~1:6 | Negative | Online Inquiry |
KO12830 | UFSP2 Knockout cell line (A549) | Human | UFSP2 | 1:3~1:4 | Negative | Online Inquiry |
UFSP2 Gene Knockout Cell Lines are a state-of-the-art research tool specifically engineered to facilitate the study of gene function and associated pathways. These cell lines have been meticulously developed using CRISPR-Cas9 technology to create precise deletions in the UFSP2 gene, a vital component thought to play a crucial role in diverse biological processes including cell signaling and metabolic pathways. By abolishing the expression of UFSP2, researchers obtain a clear model to investigate its biological roles, enabling a deeper understanding of cellular mechanisms that could have implications in various diseases.
The primary function of the UFSP2 Gene Knockout Cell Lines is to serve as a robust platform for assessing the gene's implications in disease models or therapeutic targets. The knockout of UFSP2 results in altered phenotypic characteristics and pathways, which can be rigorously analyzed for insights into its pathogenicity or functionality. As a result, these cell lines prove invaluable in the fields of molecular biology, oncology, and pharmacology, where elucidating the underlying mechanisms of gene action is critical to advancing knowledge and therapies.
The scientific importance of these cell lines cannot be understated, as they offer a highly controllable and reproducible system for experiments that can lead to significant breakthroughs in drug discovery and development. The ability to analyze the effects of the knockout facilitates innovation in gene therapy and genetic engineering approaches, making it a must-have for laboratories engaged in cutting-edge research.
What sets the UFSP2 Gene Knockout Cell Lines apart from alternatives is their reliability and ease of use. Unlike traditional models that may exhibit genetic variability, these engineered cell lines provide consistent and reproducible results, ensuring that researchers can place their trust in the data generated. Furthermore, the elimination of the UFSP2 gene is exact, minimizing off-target effects that can confound experimental outcomes.
In summary, the UFSP2 Gene Knockout Cell Lines represent a significant advancement in biological research tools designed to empower scientists and clinicians alike. Whether working to discover novel drug targets or seeking to unravel complex genetic interactions, these cell lines offer unparalleled advantages. Our company prides itself on delivering high-quality, rigorously validated biological products, backed by a team of experts committed to supporting groundbreaking research and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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