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UBXN6 Knockout Cell Lines

Gene: UBXN6

Official Full Name: UBX domain protein 6provided by HGNC

Gene Summary: Involved in ERAD pathway; endosome to lysosome transport via multivesicular body sorting pathway; and macroautophagy. Located in bounding membrane of organelle and cytosol. Part of endosome and protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05179 UBXN6 Knockout cell line (HeLa) Human UBXN6 1:3~1:6 Negative Online Inquiry
KO05180 UBXN6 Knockout cell line (HCT 116) Human UBXN6 1:2~1:4 Negative Online Inquiry
KO05181 UBXN6 Knockout cell line (HEK293) Human UBXN6 1:3~1:6 Negative Online Inquiry
KO05182 UBXN6 Knockout cell line (A549) Human UBXN6 1:3~1:4 Negative Online Inquiry

Background

UBXN6 Gene Knockout Cell Lines are specialized tools designed for biological research and therapeutic development, enabling the study of the UBXN6 gene's functional roles in cellular processes. By employing targeted CRISPR-Cas9 gene editing technology, these cell lines are engineered to lack functional UBXN6 protein, allowing researchers to examine the resulting phenotypic changes and underlying molecular mechanisms that might be influenced by this gene. This targeted knockout technique is a precise method to dissect gene function, facilitating deeper insights into cellular signaling pathways, stress responses, and protein interactions.

The scientific importance of UBXN6 Gene Knockout Cell Lines resides in their potential applications, particularly in cancer research, neurobiology, and cellular stress response studies. UBXN6 has been implicated in regulating protein homeostasis and cellular response to endoplasmic reticulum stress, making these cell lines valuable for investigating diseases associated with protein misfolding and aggregation. Furthermore, they enable researchers to identify potential therapeutic targets by understanding how loss of UBXN6 affects cell viability and function.

Compared to alternative models, such as RNA interference or chemically induced knockouts, UBXN6 Gene Knockout Cell Lines offer a more robust approach with the ability to achieve complete gene ablation. They provide consistent and reproducible results, minimizing off-target effects associated with other methods. Additionally, their availability allows for easier, high-throughput screening applications in drug discovery.

For researchers and clinicians, the ability to model diseases with these knockout lines is invaluable, as they provide mechanistic insights that can lead to novel therapeutic strategies. Our company, with a strong background in gene editing technologies and cellular biology, is committed to providing high-quality, validated cell line products that meet the evolving needs of the scientific community. By incorporating UBXN6 Gene Knockout Cell Lines into their studies, users can advance their research and contribute to groundbreaking discoveries in health and disease management.

Please note that all services are for research use only. Not intended for any clinical use.

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