Gene: UBXN2B
Official Full Name: UBX domain protein 2Bprovided by HGNC
Gene Summary: Predicted to enable ubiquitin binding activity. Involved in establishment of mitotic spindle orientation; negative regulation of protein localization to centrosome; and positive regulation of mitotic centrosome separation. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and spindle pole centrosome. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26347 | UBXN2B Knockout cell line (HeLa) | Human | UBXN2B | 1:3~1:6 | Negative | Online Inquiry |
KO26348 | UBXN2B Knockout cell line (HCT 116) | Human | UBXN2B | 1:2~1:4 | Negative | Online Inquiry |
KO26349 | UBXN2B Knockout cell line (HEK293) | Human | UBXN2B | 1:3~1:6 | Negative | Online Inquiry |
KO26350 | UBXN2B Knockout cell line (A549) | Human | UBXN2B | 1:3~1:4 | Negative | Online Inquiry |
UBXN2B Gene Knockout Cell Lines are specially developed models that enable researchers to study the functional role of the UBXN2B gene, a critical gene implicated in various cellular processes including protein degradation and response to cellular stress. Utilizing sophisticated CRISPR/Cas9 gene-editing technology, these knockout cell lines have been meticulously engineered to effectively eliminate the expression of the UBXN2B gene, providing a clean platform to investigate the gene's contributions to cellular behavior and disease mechanisms.
The primary function of these cell lines is to facilitate the study of UBXN2B's involvement in processes such as autophagy, protein homeostasis, and stress responses. By knocking out the UBXN2B gene, researchers can analyze alterations in cellular pathways that are crucial for understanding various pathologies, including cancer and neurodegenerative diseases. These cell lines serve as vital tools for elucidating the molecular underpinnings of health and disease, making them indispensable in both basic and applied biological research.
In terms of scientific importance, UBXN2B Gene Knockout Cell Lines are pivotal for translational research, allowing scientists and clinicians to develop targeted therapeutic strategies. Unlike conventional cell lines that may express varying levels of gene activity, the complete knockout of UBXN2B provides unequivocal insights into gene function, thereby enhancing the reliability of experimental results. The specificity of these models minimizes background noise and supports more robust data acquisition compared to alternative models that retain partial gene activity.
Researchers and clinicians can capitalize on the unique capabilities of these cell lines due to their ease of use and reproducibility, offering superior adaptability for experiments involving gene expression assays, drug screening, and functional assays. The precision of the knockout ensures that results are applicable to both mechanistic studies and high-throughput applications, making these lines a versatile addition to any laboratory focused on contemporary biological research.
Our expertise in developing advanced genetic models combined with a commitment to quality positions our offerings as a prime resource for laboratories seeking reliable and innovative tools for gene function investigations. The UBXN2B Gene Knockout Cell Lines represent a cornerstone in the arsenal of methodologies available to drive discovery and innovation in molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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