Home / UBE2Q1 Knockout Cell Lines

UBE2Q1 Knockout Cell Lines

Gene: UBE2Q1

Official Full Name: ubiquitin conjugating enzyme E2 Q1provided by HGNC

Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12866 UBE2Q1 Knockout cell line (HeLa) Human UBE2Q1 1:3~1:6 Negative Online Inquiry
KO12867 UBE2Q1 Knockout cell line (HCT 116) Human UBE2Q1 1:2~1:4 Negative Online Inquiry
KO12868 UBE2Q1 Knockout cell line (HEK293) Human UBE2Q1 1:3~1:6 Negative Online Inquiry
KO12869 UBE2Q1 Knockout cell line (A549) Human UBE2Q1 1:3~1:4 Negative Online Inquiry

Background

UBE2Q1 Gene Knockout Cell Lines are genetically modified cell cultures specifically designed to investigate the functional role of the UBE2Q1 gene, which encodes a member of the E2 ubiquitin-conjugating enzyme family. These cell lines enable researchers to explore the mechanistic pathways associated with ubiquitination and its impact on various cellular processes, such as protein degradation, cell cycle regulation, and stress responses. By facilitating the disruption of UBE2Q1 expression, researchers can effectively elucidate the gene’s contributions to key biological events.

The primary function of UBE2Q1 involves mediating the conjugation of ubiquitin to target proteins, thereby regulating their degradation via the proteasome. Inhibition or knockout of UBE2Q1 can result in dysregulated protein turnover, enabling scientists to study pathways involved in degenerative diseases, cancer, and metabolic disorders. Researchers utilize these knockout cell lines to perform extensive functional assays, allowing for a deeper understanding of the gene's role in cellular homeostasis and pathology.

The scientific significance of UBE2Q1 Gene Knockout Cell Lines is profound, as they present a valuable model for translational research. In clinical settings, insights gained from these models may contribute directly to the development of innovative therapeutic strategies for diseases associated with aberrant ubiquitination.

Compared to traditional models, UBE2Q1 Gene Knockout Cell Lines offer enhanced specificity and precision through targeted gene editing, allowing researchers to obtain robust and reproducible data. These cell lines are invaluable for those looking to advance their understanding of ubiquitin signaling and to unravel the complexities of cellular responses to stress and disease.

Our company specializes in providing high-quality biological products, ensuring precision and reliability in the tools necessary for advanced research. The UBE2Q1 Gene Knockout Cell Lines are a perfect example of our commitment to supporting the scientific community with innovative and effective solutions for their research needs.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.