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UBAC2 Knockout Cell Lines

Gene: UBAC2

Official Full Name: UBA domain containing 2provided by HGNC

Gene Summary: Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of retrograde protein transport, ER to cytosol. Acts upstream of or within protein localization to endoplasmic reticulum. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12888 UBAC2 Knockout cell line (HeLa) Human UBAC2 1:3~1:6 Negative Online Inquiry
KO12889 UBAC2 Knockout cell line (HCT 116) Human UBAC2 1:2~1:4 Negative Online Inquiry
KO12890 UBAC2 Knockout cell line (HEK293) Human UBAC2 1:3~1:6 Negative Online Inquiry
KO12891 UBAC2 Knockout cell line (A549) Human UBAC2 1:3~1:4 Negative Online Inquiry

Background

UBAC2 Gene Knockout Cell Lines represent a significant advancement in the field of molecular biology, providing researchers with a powerful tool to study the role of the UBAC2 gene in various cellular processes. These cell lines are genetically engineered to have a targeted disruption of the UBAC2 gene, enabling the examination of its functions in protein ubiquitination, cell signaling, and disease progression.

The mechanism of action relies on CRISPR-Cas9 gene editing technology, allowing for precise and efficient knockout of the UBAC2 gene. By eliminating the expression of this gene, researchers can investigate the resultant phenotypic changes, explore binding interactions, and elucidate the gene's involvement in pathological conditions such as cancer and neurodegenerative diseases. This provides invaluable insights into the molecular pathways influenced by UBAC2, making these cell lines invaluable for both basic and applied research.

The scientific importance of UBAC2 Gene Knockout Cell Lines is underscored by their versatility in enabling functional studies, drug discovery, and biomarker development. They can be utilized in various applications ranging from pharmacological screening to elucidating mechanisms of drug resistance, thus holding potential in improving therapeutic strategies.

Comparatively, these knockout cell lines stand out due to their specificity and user-friendly nature. Unlike traditional knockout approaches which can be labor-intensive and time-consuming, our UBAC2 knockout cell lines offer a ready-to-use solution that saves both time and resources.

For researchers and clinicians, the ability to readily access validated, reliable knockouts enables more robust experimental designs and accelerates the advancement of research initiatives, ultimately paving the way for new therapeutic developments.

Our company specializes in generating high-quality biological products, and our expertise in gene editing ensures that our UBAC2 Gene Knockout Cell Lines meet the rigorous standards required by the research community, facilitating significant contributions to the understanding of gene function and disease mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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