Gene: UBA6
Official Full Name: ubiquitin like modifier activating enzyme 6provided by HGNC
Gene Summary: Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12892 | UBA6 Knockout cell line (HeLa) | Human | UBA6 | 1:3~1:6 | Negative | Online Inquiry |
KO12893 | UBA6 Knockout cell line (HCT 116) | Human | UBA6 | 1:2~1:4 | Negative | Online Inquiry |
KO12894 | UBA6 Knockout cell line (HEK293) | Human | UBA6 | 1:3~1:6 | Negative | Online Inquiry |
KO12895 | UBA6 Knockout cell line (A549) | Human | UBA6 | 1:3~1:4 | Negative | Online Inquiry |
UBA6 Gene Knockout Cell Lines are specially engineered cellular systems designed to facilitate the study of the UBA6 gene's function and its implications in various biological processes. These knockout cell lines are generated through advanced gene-editing technologies, which precisely disrupt the UBA6 gene, rendering it non-functional. As UBA6 is involved in critical cellular processes such as ubiquitination pathways and protein degradation, the knockout models provide a powerful platform for dissecting the gene's role in proteostasis and disease mechanisms.
The primary function of UBA6 is to activate specific ubiquitin-like proteins, which are essential in regulating numerous cellular processes, including signal transduction, apoptosis, and DNA repair. By employing these knockout cell lines, researchers can observe alterations in cellular behavior, elucidate the biochemical pathways affected by the loss of UBA6, and identify potential compensatory mechanisms activated in response to its knockout.
In research and clinical settings, the significance of UBA6 Gene Knockout Cell Lines lies in their ability to provide insights into pathological conditions such as cancer, neurodegenerative disorders, and other implications of dysregulated protein homeostasis. These models allow for high-throughput screening of potential therapeutic agents and contribute to the understanding of disease progression and treatment resistance mechanisms.
One of the unique selling points of our UBA6 Gene Knockout Cell Lines is their high specificity and reproducibility. Unlike traditional methods that may yield off-target effects, our state-of-the-art CRISPR-Cas9 technology ensures precise gene editing, maximizing the reliability of experimental outcomes. Furthermore, the versatility of these knockout cell lines allows them to be used across various assays, such as functional screenings, pathway analysis, and drug response studies.
For researchers and clinicians, the value of UBA6 Gene Knockout Cell Lines is evident in the potential to accelerate discovery and innovation within the field of molecular biology. By providing an effective model system that embodies the latest advancements in genetic editing, our product not only enhances scientific inquiry but also supports the development of targeted therapies.
At our company, we pride ourselves on our expertise in producing high-quality biological products, grounded in rigorous scientific research. Our commitment to innovation and reliability ensures that we provide researchers with tools that can profoundly impact their work, paving the way for breakthroughs in understanding and treating complex diseases.
Please note that all services are for research use only. Not intended for any clinical use.
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