Home / Tmem175 Knockout Cell Lines

Tmem175 Knockout Cell Lines

Gene: TMEM175

Official Full Name: transmembrane protein 175provided by HGNC

Gene Summary: Enables arachidonate binding activity; potassium ion leak channel activity; and proton channel activity. Involved in lysosomal lumen pH elevation; potassium ion transmembrane transport; and proton transmembrane transport. Located in endosome membrane and lysosome. Is active in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01267 Tmem175 Knockout cell line (H9c2(2-1)) Rat Tmem175 Negative Online Inquiry

Background

TMEM175 Gene Knockout Cell Lines are sophisticated research tools specifically engineered to facilitate the study of TMEM175, a gene encoding a lysosomal ion channel known to be involved in cellular homeostasis and autophagy. These cell lines are generated using advanced CRISPR-Cas9 gene editing technologies, allowing for precise and permanent disruption of the TMEM175 gene. This knockout model serves as a crucial instrument for elucidating the biological functions of TMEM175 and its implications in various physiological and pathological contexts.

The primary mechanism of the TMEM175 knockout cell lines lies in their ability to create a loss-of-function scenario for the TMEM175 gene, facilitating researchers to investigate the myriad effects associated with its absence. This includes assessments of lysosomal function, ion homeostasis, and autophagic processes, providing insights into how dysregulation of these pathways contributes to diseases such as neurodegeneration and lysosomal storage disorders.

Scientifically, the TMEM175 Gene Knockout Cell Lines hold exceptional promise in both basic and applied research settings. They can be used to model diseases, screening pharmaceuticals, or deciphering metabolic pathways, making them invaluable for academic laboratories and pharmaceutical companies alike. Their application spans from elucidating biochemical pathways to validating drug targets, thereby contributing to newfound therapies and interventions.

What sets these cell lines apart from alternatives is their robustness, flexibility, and user-friendly protocol. Unlike standard knockout methods that may result in off-target effects, the CRISPR-Cas9 technology used ensures high specificity and efficiency. Furthermore, these cell lines can be easily cultured and maintained, significantly reducing the experimental burden on researchers.

For researchers, clinicians, and biopharmaceutical professionals, the TMEM175 Gene Knockout Cell Lines represent a unique opportunity to decode the complexities of cellular mechanisms linked to TMEM175 and their implications for human health. Utilizing these products can accelerate research timelines and enhance the precision of experimental outcomes.

Our company specializes in cutting-edge genetic engineering solutions, equipped with the expertise to deliver high-quality biological products such as TMEM175 Gene Knockout Cell Lines, tailored to your research needs and advancing the frontiers of biomedical discovery.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.