Gene: Tead4
Official Full Name: TEA domain family member 4provided by MGI
Gene Summary: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. This factor may play a role in the embryonic development of skeletal muscle. Alternatively spliced transcripts encoding distinct isoforms, which are translated through the use of a non-AUG (AUU) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01211 | Tead4 Knockout cell line(CT26.WT) | Mouse | Tead4 | 1:3~1:4 | Negative | Online Inquiry |
Tead4 Gene Knockout Cell Lines are genetically modified cell lines characterized by the targeted deletion of the Tead4 gene, which encodes a transcription factor critical for various cellular processes, including development, differentiation, and cell proliferation. By specifically knocking out this gene, researchers can explore the downstream effects on gene expression, cell signaling pathways, and developmental biology.
The functionality of these cell lines is rooted in their ability to model the loss of Tead4 activity in a controlled setting. The knockout mechanism is achieved through advanced CRISPR-Cas9 technology, which enables precise edits to the genome. This results in a lack of Tead4 function, allowing researchers to investigate how its absence impacts cellular behaviors and roles in critical processes like organogenesis and tissue homeostasis. Furthermore, these cell lines serve as invaluable tools for studying diseases such as cancer, where Tead4 may play a regulatory role.
From a scientific standpoint, the Tead4 Gene Knockout Cell Lines are indispensable in both basic research and clinical applications. They provide insights into the mechanistic underpinnings of key biological processes and offer a platform for drug discovery, particularly in targeting pathways involving cell growth and differentiation. Compared to traditional methods of gene manipulation, such as RNA interference, these knockout cell lines provide a more stable and lasting physiological model, leading to more reproducible and reliable results.
The unique selling points of Tead4 Gene Knockout Cell Lines lie in their specificity, reliability, and the thorough characterization provided, making them a superior choice for researchers delving into gene function and its implications in various biological contexts. Researchers, clinicians, and biologists will find significant value in utilizing these models to advance their understanding of complex cellular dynamics and therapeutic avenues.
Our company prides itself on a commitment to excellence in developing high-quality genetic products that empower scientists and researchers to push the boundaries of knowledge in genetics and molecular biology. With a focus on rigorous validation and robust customer support, we offer products that are not just tools, but essential resources for innovative research.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.