Gene: TYW3
Official Full Name: tRNA-yW synthesizing protein 3 homologprovided by HGNC
Gene Summary: Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27093 | TYW3 Knockout cell line (HeLa) | Human | TYW3 | 1:3~1:6 | Negative | Online Inquiry |
KO27094 | TYW3 Knockout cell line (HCT 116) | Human | TYW3 | 1:2~1:4 | Negative | Online Inquiry |
KO27095 | TYW3 Knockout cell line (HEK293) | Human | TYW3 | 1:3~1:6 | Negative | Online Inquiry |
KO27096 | TYW3 Knockout cell line (A549) | Human | TYW3 | 1:3~1:4 | Negative | Online Inquiry |
TYW3 Gene Knockout Cell Lines are specialized cell lines that have been genetically modified to disrupt the expression of the TYW3 gene, which is implicated in the biosynthesis of certain tRNA modifications. These cell lines serve as invaluable tools for studying the functional role of TYW3 in cellular metabolism, protein synthesis, and stress responses related to mitochondrial function and cellular homeostasis. By utilizing CRISPR/Cas9 technology or similar gene-editing techniques, our TYW3 Gene Knockout Cell Lines enable researchers to create specific, reproducible models that dissect the nuances of gene function and interactome within both normal and pathological contexts.
The primary function of these knockout cell lines lies in their ability to isolate and study the resultant phenotypic changes following the loss of TYW3 activity. Researchers utilize these models to investigate the consequences on cellular behavior, enzymatic activity, and overall gene expression profiles. Insights gained from such studies can facilitate a deeper understanding of mitochondrial diseases, potential metabolic disorders, and cellular responses under stress conditions, thereby enriching the biomedical research landscape.
The scientific importance of TYW3 Gene Knockout Cell Lines is clear; they enable both foundational research and translational applications in drug discovery, genetic therapy, and precision medicine. By elucidating the role of the TYW3 gene in various biological pathways, researchers can identify potential therapeutic targets and develop novel treatment strategies for complex diseases.
Compared to traditional cell lines, which may not exhibit the same functional characteristics, TYW3 Gene Knockout Cell Lines provide specificity and reliability. Their tailored genetic makeup reduces background noise in experimental designs and leads to clearer, more interpretable results. This level of precision is particularly crucial for experiments requiring accurate modeling of complex biological systems.
For researchers and clinicians alike, the value of TYW3 Gene Knockout Cell Lines lies in their potential to drive breakthroughs in understanding disease mechanisms and identifying new therapeutic avenues. Our commitment to high-quality genetic materials ensures that our products are not only robust and reliable but also backed by extensive validation and research.
With years of expertise in biological and genetic research products, our company stands at the forefront of the field, providing innovative solutions that empower scientific inquiry and advance clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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