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TTC4 Knockout Cell Lines

Gene: TTC4

Official Full Name: tetratricopeptide repeat domain 4provided by HGNC

Gene Summary: This gene encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. The encoded protein interacts with heat shock proteins 70 and 90. Alternative splicing results in multiple transcript variants. Naturally-occuring readthrough transcription occurs from upstream gene MROH (maestro heat-like repeat family member 7) to this gene. [provided by RefSeq, Apr 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34913 TTC4 Knockout cell line (HeLa) Human TTC4 1:3~1:6 Negative Online Inquiry
KO34914 TTC4 Knockout cell line (HCT 116) Human TTC4 1:2~1:4 Negative Online Inquiry
KO34915 TTC4 Knockout cell line (HEK293) Human TTC4 1:3~1:6 Negative Online Inquiry

Background

TTC4 Gene Knockout Cell Lines are specialized cellular models developed through precise genetic engineering techniques to disable the TTC4 gene, which encodes for a protein involved in several cellular processes such as growth, differentiation, and stress response. By systematically knocking out the TTC4 gene, these cell lines provide an invaluable tool for investigating the functional implications of TTC4 in various biological contexts.

The mechanism underlying these cell lines involves the targeted disruption of the TTC4 gene using advanced CRISPR-Cas9 technology, allowing researchers to create specific gene knockouts with high efficiency and accuracy. By eliminating the expression of the TTC4 protein, scientists can study downstream signaling pathways and cellular responses, offering pivotal insights into its role in disease mechanisms, particularly in cancer biology and metabolic disorders.

The scientific significance of TTC4 Gene Knockout Cell Lines lies in their application across both research and clinical settings, enabling studies that can lead to the development of novel therapeutic strategies. These models serve as platforms for drug screening and functional genomics, thus facilitating the identification of potential pharmacological targets and biomarkers for disease progression.

What sets TTC4 Gene Knockout Cell Lines apart from alternative products is their optimized performance in various assays, including proliferation, apoptosis, and migration studies. Furthermore, these cell lines come with comprehensive validation data, ensuring reliability and reproducibility in research findings. The ease of use and implementation into existing experimental frameworks promote their integration in diverse study designs, making them a favorite among researchers and clinicians.

In summary, TTC4 Gene Knockout Cell Lines represent a significant advancement in the field of molecular biology, providing researchers with the means to dissect the complexities of gene function, contributing to a richer understanding of pathophysiology. Our company prides itself on its commitment to quality and innovation, offering a range of cutting-edge biological products designed to enhance research capabilities and support scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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