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TTC39B Knockout Cell Lines

Gene: TTC39B

Official Full Name: tetratricopeptide repeat domain 39Bprovided by HGNC

Gene Summary: Predicted to be involved in several processes, including cholesterol homeostasis; negative regulation of cholesterol storage; and regulation of cholesterol efflux. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03578 TTC39B Knockout cell line (HeLa) Human TTC39B 1:3~1:6 Negative Online Inquiry
KO03579 TTC39B Knockout cell line (HCT 116) Human TTC39B 1:2~1:4 Negative Online Inquiry
KO03580 TTC39B Knockout cell line (HEK293) Human TTC39B 1:3~1:6 Negative Online Inquiry
KO03581 TTC39B Knockout cell line (A549) Human TTC39B 1:3~1:4 Negative Online Inquiry

Background

TTC39B Gene Knockout Cell Lines are genetically engineered cellular models designed specifically for the study of the TTC39B gene, which plays a critical role in cellular processes such as endosomal trafficking and lipid metabolism. By utilizing CRISPR/Cas9 technology, these knockout cell lines are rendered deficient in TTC39B expression, providing researchers with a valuable tool for investigating the gene’s physiological and pathological roles.

The primary function of these knockout cell lines is to enable detailed analysis of the loss-of-function effects associated with TTC39B. Researchers can explore changes in cellular processes, protein interactions, and signaling pathways that are influenced by the absence of this gene. This is particularly significant in understanding conditions such as metabolic disorders or neurodegenerative diseases where lipid metabolism and trafficking are disrupted.

From a scientific standpoint, the TTC39B Gene Knockout Cell Lines are indispensable within both research and clinical environments. They allow scientists to elucidate the gene's involvement in various biological pathways, paving the way for potential therapeutic interventions. In clinical settings, insights garnered from these models can inform the development of targeted therapies for diseases linked to aberrations in cellular trafficking and metabolism.

One of the key advantages of our TTC39B Gene Knockout Cell Lines is their high specificity and reproducibility, coupled with the ease of use in a variety of laboratory settings. Unlike alternative systems, these lines provide a direct assay for functional analysis of the gene without compensatory effects that may arise from partial knockdowns or overexpression models. Moreover, they are validated for consistent performance across different experiments, making them a reliable asset for any research focus.

For researchers, clinicians, and biotechnology firms alike, this product represents an opportunity to gain unprecedented insights into the function and implications of the TTC39B gene. As a reputable leader in providing cutting-edge biological products, our company is committed to supporting the scientific community in advancing research and therapeutic developments through high-quality and innovative cell line solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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