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TSPAN3 Knockout Cell Lines

Gene: TSPAN3

Official Full Name: tetraspanin 3provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Dec 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32291 TSPAN3 Knockout cell line (HeLa) Human TSPAN3 1:3~1:6 Negative Online Inquiry
KO32292 TSPAN3 Knockout cell line (HCT 116) Human TSPAN3 1:2~1:4 Negative Online Inquiry
KO32293 TSPAN3 Knockout cell line (HEK293) Human TSPAN3 1:3~1:6 Negative Online Inquiry
KO32294 TSPAN3 Knockout cell line (A549) Human TSPAN3 1:3~1:4 Negative Online Inquiry

Background

TSPAN3 Gene Knockout Cell Lines are specially engineered cell lines in which the TSPAN3 gene has been completely inactivated through targeted gene editing techniques, such as CRISPR-Cas9. This allows researchers to study the biological effects of TSPAN3 loss, providing insights into its role in physiological and pathological processes. TSPAN3 (Tetraspanin 3) is involved in multiple cellular functions, including cell signaling, adhesion, and the modulation of immune responses. By utilizing these knockout cell lines, scientists can investigate the implications of TSPAN3 deficiency in various biological contexts and disease models.

The primary function of the TSPAN3 gene is to facilitate interactions between membrane proteins, significantly influencing cellular communication and behavior. Knockout cell lines enable the systematic examination of alterations in signaling pathways and cellular responses, thereby aiding in the understanding of cancer metastasis, inflammation, and other disorders linked to TSPAN3 dysregulation. In clinical settings, insights gained from using these models can inform potential therapeutic targets, paving the way for the development of innovative treatment strategies.

Compared to other gene-editing technologies, our TSPAN3 Gene Knockout Cell Lines offer a high degree of specificity, reproducibility, and ease of use. Traditional methods may face challenges related to off-target effects or varied gene knockout efficiencies, but our products are validated for consistent performance and accuracy. This reliability is pivotal for researchers seeking to draw conclusive results from their studies, enhancing research productivity and advancing scientific knowledge.

The value of TSPAN3 Gene Knockout Cell Lines extends beyond merely facilitating research; they empower scientists to uncover novel molecular mechanisms and propose actionable insights in the clinical domain. Researchers and clinicians can leverage these resources to enhance their understanding of TSPAN3-related functions and explore their therapeutic implications, ultimately contributing to improved patient outcomes.

Our company prides itself on its extensive expertise in genetic engineering and cellular technology. With a commitment to quality and innovation, we provide a diverse portfolio of biological products designed to meet the evolving needs of the research community, ensuring that our customers have access to top-tier tools for their groundbreaking work.

Please note that all services are for research use only. Not intended for any clinical use.

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