Gene: TSPAN2
Official Full Name: tetraspanin 2provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32288 | TSPAN2 Knockout cell line (HeLa) | Human | TSPAN2 | 1:3~1:6 | Negative | Online Inquiry |
KO32289 | TSPAN2 Knockout cell line (HEK293) | Human | TSPAN2 | 1:3~1:6 | Negative | Online Inquiry |
KO32290 | TSPAN2 Knockout cell line (A549) | Human | TSPAN2 | 1:3~1:4 | Negative | Online Inquiry |
TSPAN2 Gene Knockout Cell Lines are genetically engineered cell models that have had the TSPAN2 gene selectively disrupted, leading to an invaluable resource for studying the gene’s role in cellular functions and disease mechanisms. TSPAN2, known for its involvement in immunological processes and cell signaling pathways, plays a significant role in various cellular interactions and functions. These knockout cell lines enable researchers to explore the specific contributions of TSPAN2, as well as its interactions with other biomolecules, thereby providing insights into both normal cellular physiology and pathophysiological conditions.
The primary mechanism behind the effectiveness of TSPAN2 knockout cell lines is the complete absence of functional TSPAN2 protein, allowing for an unmasked study of compensatory pathways and alternative signaling mechanisms that may come into play in its absence. This model is particularly useful in dissecting the role of TSPAN2 in processes such as cell adhesion, migration, and immune response, making it a valuable tool in both research and clinical investigations.
Scientifically, TSPAN2 knockout cell lines have extensive applications, especially in cancer research, autoimmune diseases, and therapeutic development. By enabling the examination of TSPAN2's specific contributions, these cell lines assist in identifying potential therapeutic targets and biomarkers, providing researchers with crucial data that can lead to novel treatment strategies.
Compared to alternative models, TSPAN2 knockout cell lines offer a higher specificity and focus, allowing for precise genetic manipulation without the confounding effects seen in whole-organism studies. Furthermore, they can be easily cultured and maintained, streamlining experimental workflows. The ability to readily assess the effects of gene loss offers unprecedented insight into the biological pathways at work, making these cell lines a preferred choice for cutting-edge research.
Ultimately, TSPAN2 Gene Knockout Cell Lines stand as a testament to our company's commitment to providing high-quality, innovative research tools. Our deep expertise in genetic engineering and cell line development ensures that our products support scientists and clinicians in their quest to advance understanding and treatment of complex diseases. By choosing our offerings, researchers invest in reliability and excellence at the forefront of biological and biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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