Gene: TSKU
Official Full Name: tsukushi, small leucine rich proteoglycanprovided by HGNC
Gene Summary: Predicted to enable transforming growth factor beta binding activity. Predicted to be involved in several processes, including cholesterol efflux; cholesterol homeostasis; and nervous system development. Predicted to act upstream of or within several processes, including ciliary body morphogenesis; negative regulation of Wnt signaling pathway; and telencephalon development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28520 | TSKU Knockout cell line (HeLa) | Human | TSKU | 1:3~1:6 | Negative | Online Inquiry |
KO28521 | TSKU Knockout cell line (HCT 116) | Human | TSKU | 1:2~1:4 | Negative | Online Inquiry |
KO28522 | TSKU Knockout cell line (HEK293) | Human | TSKU | 1:3~1:6 | Negative | Online Inquiry |
KO28523 | TSKU Knockout cell line (A549) | Human | TSKU | 1:3~1:4 | Negative | Online Inquiry |
TSKU Gene Knockout Cell Lines are specialized cell lines engineered to lack functional copies of the TSKU gene. These models enable researchers to study the specific roles of TSKU in various biological processes, including cellular signaling, metabolism, and development. By establishing a clear connection between gene function and cellular phenotype, TSKU Gene Knockout Cell Lines serve as invaluable tools for dissecting gene function through loss-of-function analysis.
The primary mechanism of action in these knockout cell lines involves the precise deletion of TSKU gene sequences using state-of-the-art gene-editing technologies such as CRISPR-Cas9 or homologous recombination. By creating a definitive gene deficiency, researchers can assess alterations in gene expression, protein interactions, and cell behavior, offering insights into the underlying pathways affected by TSKU loss. This functional approach is integral to advancing knowledge in fields such as cancer research, immunology, and developmental biology.
The scientific importance of TSKU Gene Knockout Cell Lines is underscored by their diverse applications in both research and clinical settings. They facilitate the identification of novel therapeutic targets, assess drug efficacy, and contribute to biomarker discovery, ultimately enhancing our understanding of disease mechanisms. In the realm of regenerative medicine, these tools support the evaluation of potential interventions based on TSKU's role in cellular differentiation and maintenance.
One of the standout advantages of TSKU Gene Knockout Cell Lines compared to traditional research methodologies is their specificity and reliability. Unlike chemical inhibitors or RNA interference techniques, which may affect multiple pathways, these cell lines provide a defined genetic background, ensuring findings are directly attributable to the genetic modification. This level of precision makes them ideal for reproducible experiments and high-quality data generation.
For researchers, clinicians, and biotechnologists, TSKU Gene Knockout Cell Lines offer a unique opportunity to explore fundamental biological questions with enhanced accuracy and depth. The value of these models lies not only in their utility for advancing scientific inquiry but also in driving therapeutic innovation.
At [Your Company Name], we possess extensive expertise in genetic engineering and cell line development. Our commitment to providing high-quality, reliable biological products ensures that our customers are equipped with the tools needed to push the boundaries of research and clinical science.
Please note that all services are for research use only. Not intended for any clinical use.
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