Gene: TRMT61B
Official Full Name: tRNA methyltransferase 61Bprovided by HGNC
Gene Summary: Enables mRNA (adenine-N1-)-methyltransferase activity; rRNA (adenine) methyltransferase activity; and tRNA (adenine(58)-N1)-methyltransferase activity. Involved in mRNA processing and mitochondrial tRNA processing. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13006 | TRMT61B Knockout cell line (HeLa) | Human | TRMT61B | 1:3~1:6 | Negative | Online Inquiry |
KO13007 | TRMT61B Knockout cell line (HCT 116) | Human | TRMT61B | 1:2~1:4 | Negative | Online Inquiry |
KO13008 | TRMT61B Knockout cell line (HEK293) | Human | TRMT61B | 1:3~1:6 | Negative | Online Inquiry |
KO13009 | TRMT61B Knockout cell line (A549) | Human | TRMT61B | 1:3~1:4 | Negative | Online Inquiry |
TRMT61B Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the TRMT61B gene, which plays a pivotal role in the biological processes of ribosomal RNA methylation and cellular metabolism. These knockout cell lines are created using sophisticated gene editing technologies, such as CRISPR-Cas9, to disrupt the TRMT61B gene function, allowing researchers to investigate the resulting phenotypic and molecular changes that manifest upon its loss.
The primary function of these cell lines lies in elucidating the gene’s role in cellular pathways and how its dysregulation could contribute to various diseases, including cancer and metabolic disorders. By studying TRMT61B knockout cells, researchers can gain insights into ribosome biogenesis and its implications in cellular stress responses, ultimately contributing to the broader understanding of gene regulation and function.
Scientifically, the TRMT61B Gene Knockout Cell Lines have critical applications in both basic research and translational studies. Their ability to model gene loss allows for investigations into new therapeutic targets and biomarker development, making them invaluable tools in drug discovery and disease modeling. Unlike conventional models, these knockout lines provide a more precise representation of gene function by eliminating the confounding effects seen in other experimental approaches.
What sets TRMT61B Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, coupled with the capability for easy manipulation to create diverse experimental conditions. This versatility enhances their utility across various research disciplines, providing researchers with the nuanced understanding needed for innovative solutions.
For researchers and clinicians, these cell lines represent an indispensable resource that not only streamlines the exploration of TRMT61B’s biological roles but also supports the development of novel therapeutic strategies. The ability to dissect complex biological processes at the cellular level makes them essential in advancing our understanding of human health and disease.
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Please note that all services are for research use only. Not intended for any clinical use.
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