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TRIT1 Knockout Cell Lines

Gene: TRIT1

Official Full Name: tRNA isopentenyltransferase 1provided by HGNC

Gene Summary: This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13030 TRIT1 Knockout cell line (HeLa) Human TRIT1 1:3~1:6 Negative Online Inquiry
KO13031 TRIT1 Knockout cell line (HCT 116) Human TRIT1 1:2~1:4 Negative Online Inquiry
KO13032 TRIT1 Knockout cell line (HEK293) Human TRIT1 1:3~1:6 Negative Online Inquiry
KO13033 TRIT1 Knockout cell line (A549) Human TRIT1 1:3~1:4 Negative Online Inquiry

Background

TRIT1 Gene Knockout Cell Lines represent a cutting-edge tool in genetic and cellular biology research, specifically engineered to study the function and regulation of the TRIT1 gene, which is implicated in tRNA-related processes. These cell lines are created using advanced CRISPR technology to produce a precise knockout of the TRIT1 gene, allowing researchers to investigate its role in cellular metabolism, protein synthesis, and potential contributions to various diseases.

The primary mechanism through which these knockout cell lines operate involves the deliberate disruption of the TRIT1 gene, leading to the absence of its corresponding protein and alterations in the associated biochemical pathways. This enables scientists to dissect the functional consequences of TRIT1 loss, providing insights into the molecular mechanisms that underpin cellular responses to stress, development, or pathogenesis.

In scientific research and clinical applications, TRIT1 Gene Knockout Cell Lines offer invaluable resources for elucidating the complexities of gene regulation and cellular homeostasis. By facilitating the examination of gene function in a controlled environment, these cell lines serve as a vital asset for developing targeted therapies, understanding genetic disorders, and exploring genetic interactions within metabolic pathways.

Compared to traditional methods, the use of TRIT1 knockout cell lines is advantageous due to their precise genetic modification, reproducibility in experimental setups, and ease of application across various in vitro assays. Researchers gain a more refined understanding of gene function dynamics, which is often challenging to achieve with alternative methods such as RNA interference.

For researchers, clinicians, and biotechnologists, the TRIT1 Gene Knockout Cell Lines are an essential resource that embodies the convergence of genetics and applied biological research. Their ability to provide clear insights into gene function and regulatory mechanisms makes them a critical component of both basic and translational research efforts.

Our company prides itself on pioneering innovative biological products and technologies. With a focus on precision, reliability, and advancing scientific knowledge, we continually strive to support the research community with tools that facilitate groundbreaking discoveries and enhance clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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