Gene: TRIM47
Official Full Name: tripartite motif containing 47provided by HGNC
Gene Summary: Enables ubiquitin protein ligase activity. Involved in protein ubiquitination. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23547 | TRIM47 Knockout cell line (HeLa) | Human | TRIM47 | 1:3~1:6 | Negative | Online Inquiry |
KO23548 | TRIM47 Knockout cell line (HCT 116) | Human | TRIM47 | 1:2~1:4 | Negative | Online Inquiry |
KO23549 | TRIM47 Knockout cell line (HEK293) | Human | TRIM47 | 1:3~1:6 | Negative | Online Inquiry |
KO23550 | TRIM47 Knockout cell line (A549) | Human | TRIM47 | 1:3~1:4 | Negative | Online Inquiry |
TRIM47 Gene Knockout Cell Lines are highly specialized biological tools designed to facilitate advanced research into the TRIM47 gene's role in cellular processes. The TRIM47 gene encodes a member of the tripartite motif-containing (TRIM) protein family, which is implicated in various cellular mechanisms, including protein degradation, cellular signaling, and immune responses. These knockout cell lines utilize CRISPR/Cas9 technology to effectively disrupt the expression of TRIM47, allowing researchers to study its function and the subsequent effects on cellular behavior.
The primary mechanism of action involves the precise editing of the TRIM47 gene, leading to a lack of functional protein. By comparing the knockout cell lines to their wild-type counterparts, researchers can glean insights into the gene's influence on pathways such as tumorigenesis, cell cycle regulation, and apoptosis. This functional analysis is crucial, as it aids in deciphering the underlying mechanisms of diseases such as cancer, neurological disorders, and autoimmune conditions, making these cell lines invaluable in both basic and applied research contexts.
The scientific importance of TRIM47 knockout cell lines is underpinned by their ability to elucidate the biological significance of TRIM47 in different pathophysiological scenarios. They are particularly advantageous in drug discovery and development, providing a valuable platform for screening potential therapeutics targeting TRIM47-related pathways. Additionally, their ability to generate meaningful data for in vitro experiments enhances reproducibility and reliability, which are often challenging aspects in biological research.
What sets TRIM47 Gene Knockout Cell Lines apart from alternative products is their high specificity and robust performance validated through extensive testing. Researchers can be confident in the fidelity of these models, knowing that they effectively replicate loss-of-function scenarios. Furthermore, these cell lines come with comprehensive technical support and detailed protocols, streamlining the experimentation process.
In conclusion, TRIM47 Gene Knockout Cell Lines represent a critical resource for researchers and clinicians who are exploring the frontiers of genetic understanding and therapeutic intervention. By choosing our products, you are not only accessing cutting-edge biological tools but also leveraging our company’s deep expertise in genetic engineering and molecular biology, ensuring your research is supported by reliable and innovative solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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