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TRIM4 Knockout Cell Lines

Gene: TRIM4

Official Full Name: tripartite motif containing 4provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.[provided by RefSeq, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24001 TRIM4 Knockout cell line (HeLa) Human TRIM4 1:3~1:6 Negative Online Inquiry
KO24002 TRIM4 Knockout cell line (HCT 116) Human TRIM4 1:2~1:4 Negative Online Inquiry
KO24003 TRIM4 Knockout cell line (HEK293) Human TRIM4 1:3~1:6 Negative Online Inquiry
KO24004 TRIM4 Knockout cell line (A549) Human TRIM4 1:3~1:4 Negative Online Inquiry

Background

TRIM4 Gene Knockout Cell Lines are advanced biological reagents that have been engineered to specifically eliminate the expression of the TRIM4 gene, a member of the tripartite motif-containing protein family known for its involvement in various cellular processes, including immune response regulation and cellular signaling pathways. These knockout cell lines serve as powerful tools in molecular biology research, enabling scientists to investigate the precise role of TRIM4 in biological systems and its implications in diseases such as cancer and autoimmune disorders.

The mechanism of action of TRIM4 Gene Knockout Cell Lines involves the targeted disruption of the TRIM4 gene using cutting-edge genome-editing technologies, such as CRISPR-Cas9. This approach results in a complete lack of TRIM4 protein expression, facilitating studies to uncover how its absence affects cellular behavior, signaling cascades, and gene expression profiles. These insights are vital for understanding the molecular underpinnings of diseases and for identifying potential therapeutic targets.

The scientific importance of these knockout cell lines cannot be overstated. They are invaluable in both academic research and clinical settings, paving the way for groundbreaking discoveries in the fields of immunology, oncology, and pharmacology. By utilizing TRIM4 knockout models, researchers can explore novel pathways and mechanisms, ultimately contributing to the development of targeted therapies and advancements in personalized medicine.

One of the distinctive advantages of TRIM4 Gene Knockout Cell Lines is their reliability and reproducibility compared to other knockout models, such as those generated by traditional homologous recombination. In addition, these cell lines are meticulously characterized to ensure consistent performance across experiments, allowing researchers to achieve high-confidence results. This reliability, combined with the ease of use and versatility of these cell lines in various experimental setups, significantly enhances their appeal to the scientific community.

For researchers and clinicians aiming to deepen their understanding of TRIM4's biological roles or develop new therapeutic strategies, TRIM4 Gene Knockout Cell Lines offer a compelling solution. Our company specializes in the production of high-quality genetic tools, with a commitment to delivering innovative products that accelerate research and improve patient outcomes. With our expertise in cutting-edge genome editing techniques and a robust portfolio of biological reagents, we are positioned to support the scientific community in their quest for knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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